Evidence mapPaperPMID 41708966Full record

SynthesisEuropean journal of clinical nutrition2026

Body mass index and activities of daily living impairment: systematic review and meta-analysis.

Md Razib Mamun, Hanson Gabriel Nuamah, Young-Jae Hong, Zean Song, Tahmina Akter, Yuko Yoshida, Yoshihisa Nakano, K M Saif-Ur-Rahman, Hiroshi Yatsuya, Rei Otsuka

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in European journal of clinical nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Md Razib MamunDepartment of Public Health and Health Systems, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Hanson Gabriel NuamahDepartment of Public Health and Health Systems, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Young-Jae HongDepartment of Public Health and Health Systems, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Zean SongDepartment of Public Health and Health Systems, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Tahmina AkterDepartment of Public Health and Health Systems, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Yuko YoshidaDepartment of Public Health and Health Systems, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Yoshihisa NakanoDepartment of Public Health and Health Systems, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
K M Saif-Ur-RahmanCollege of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland.
Hiroshi YatsuyaDepartment of Public Health and Health Systems, Graduate School of Medicine, Nagoya University, Nagoya, Japan. h828@med.nagoya-u.ac.jp.ORCID http://orcid.org/0000-0002-6220-9251
Rei OtsukaDepartment of Epidemiology of Aging, National Center for Geriatrics and Gerontology, Aichi, Japan.ORCID http://orcid.org/0000-0001-6184-570X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both underweight and obesity have been linked to increased risk of disability, yet evidence on the relationship between body mass index (BMI) and activities of daily living (ADL) impairment remains inconsistent. To examine these associations in adults, we conducted this systematic review and meta-analysis following the standard methods and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. Six databases were searched from inception to August 12, 2024. The protocol is registered in the PROSPERO (CRD42022357046). Abstracts and full-text articles describing associations between BMI and ADL impairment were screened using Rayyan software. Study quality was assessed using the RoBANS tool. A random-effects model meta-analysis was performed using metaanalysisonline, a web-based meta-analytic platform, with BMI categories of <18.5 (underweight), 25-29.9 (overweight), and ≥30 (obese) as exposures, and 18.5-24.9 (normal) as the reference. Of the initial 25,212 articles identified, 132 studies met the inclusion criteria. The meta-analysis showed positive association in both longitudinal studies [odds ratio (OR) 1.77, 95% confidence interval (CI): 1.54-2.03] and cross-sectional studies (OR: 1.56, 95% CI: 1.38-1.76). Overweight individuals exhibited a moderate increase in ADL risk in longitudinal studies (OR: 1.19, 95% CI: 1.09-1.30), but not in cross-sectional studies (OR: 1.06, 95% CI: 0.95-1.18). Both longitudinal and cross-sectional studies revealed a positive association between underweight participants and ADL impairment (OR: 1.20, 95% CI: 1.02-1.42; OR: 1.46, 95% CI: 1.24-1.72, respectively). Individuals with higher BMI, as well as those who are underweight, are at increased risk of ADL limitations.

Indexed as

Activities of Daily LivingBody Mass IndexObesityThinnessHumansOverweightRisk Factors

Identifiers

PMID41708966
PMCPMC13186705

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.