ReviewTropical medicine and health2026
In vitro cytotoxicity of medicinal plants used in prostate cancer management in Africa: a systematic review.
Review in Tropical medicine and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProstate cancer in Africa is a significant public health problem with a consistently increasing high mortality rate. The World Health Organization (WHO) estimates that 80% of the population in Africa uses herbal medicines. However, research on the cytotoxicity related to African plant extracts against prostate cancer is still limited, which retards the development of potential anticancer agents from these plants. This review compiles data on the cytotoxicity of African medicinal plants used in the management of prostate cancer.
methodsA systematic literature review search was conducted from January 2015 to June 2025 on studies on the cytotoxic activity of medicinal plants used in the management of prostate cancer in Africa. The review was based on the Preferred Reporting Items for the Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The study considered cytotoxic studies available on the search engines of ScienceDirect, Google scholar, Web of Science, SpringerLink, Scopus, PubMed, BioMed, and Scientific Electronic Library Online (SciELO). The data were analysed using SPSS statistical software.
resultsTwenty-eight articles on cytotoxic activity of anti-prostate cancer medicinal plants in Africa were evaluated. The studies reported 45 medicinal plants with cytotoxic activity against prostate cancer cell lines. The extract of Dichrostachys cinerea with IC
conclusionThe investigated medicinal plants contain bioactive compounds that exhibited cytotoxic activity against prostate cancer cell lines. The bioactive compounds found in these plants could be used in clinical trials in the development of prostate cancer therapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.