Evidence map›Paper›PMID 41709360›Full record

ArticleInfectious diseases of poverty2026

Psychosocial and behavioral correlates of Mpox infection among men who have sex with men in China: a multicenter cross-sectional study with implications for health equity.

Gang Xu, Changyuan Zhou, Yuxuan Hua, Shangbin Liu, Jianyu Chen, Ying Wang, Jiechen Zhang, Yong Cai

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Infectious diseases of poverty, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Gang Xu *Public Health Department, Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Changyuan Zhou *Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, Beijing, 100191, China.
Yuxuan Hua *School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Shangbin Liu *Public Health Department, Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Jianyu ChenCollege of Public Health, Shanghai University of Medicine and Health Sciences, Shanghai, 200025, China.
Ying WangPublic Health Department, Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Jiechen ZhangDermatology Department, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. zjc4778@shtrhospital.com.
Yong CaiPublic Health Department, Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. caiyong202028@sjtu.edu.cn.

Funding

Changning District Medical and Health Research Special Project CNKW2022Y08Key discipline projects of Shanghai Three-Year Action Plan for Public Health GWVI-11.1-29Public Health Research Project from Shanghai Disease Control and Prevention Administration 2024GKM30Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine TRYJ2024LC13, TRYJ2022LC10
6 · The paper itself

Abstract

backgroundMpox (formerly known as monkeypox) has disproportionately affected men who have sex with men (MSM), yet evidence from East Asia on psychosocial and behavioral correlates is limited. We examined factors associated with Mpox infection among MSM in China, with attention to health equity considerations.

methodsA multi-center cross-sectional survey was conducted in six Chinese cities (November 2023-March 2024). Eligible MSM (≥ 18 years; male-to-male sexual contact in the past six months) completed an anonymous questionnaire capturing sociodemographics, Human Immunodeficiency Virus (HIV) infection status (along with other health statuses like hypertension, diabetes, and hyperlipidemia), unprotected anal intercourse (UAI), multiple sex partnerships (MSP), pre-sex substance use (alcohol and drugs), recent voluntary counseling and testing for HIV (VCT), and psychosocial measures (perceived discrimination and self-esteem). Mpox infection was ascertained by self-reported clinical diagnosis or syndromic criteria aligned with national guidance. Multivariable logistic regression estimated adjusted odds ratios (aOR) and 95% confidence intervals (CI). False discovery rate was controlled using the Benjamini-Hochberg procedure within prespecified hypothesis families.

resultsAmong 2403 participants (mean age 30.6 years), 5.9% met the Mpox case definition. In multivariable logistic regression analyses, younger men had the highest odds of Mpox infection. Using ages 18-24 years as the reference, older groups showed significantly lower odds: 25-34 years (OR = 0.508, 95% CI 0.317-0.814, P = 0.005), 35-44 years (OR = 0.142, 95% CI 0.064-0.316, P < 0.001), and ≥ 45 years (OR = 0.170, 95% CI 0.045-0.641, P = 0.009). Behavioral and health correlates that significantly increased the odds of Mpox included UAI (OR = 2.841, 95% CI 1.858-4.345, P < 0.001), MSP (OR = 1.586, 95% CI 1.063-2.368, P = 0.024), pre-sex drug use (OR = 2.359, 95% CI 1.199-4.639, P = 0.013), and pre-sex alcohol use (OR = 3.955, 95% CI 2.530-6.181, P < 0.001). Furthermore, recent VCT participation was positively associated with Mpox (OR = 2.079, 95% CI 1.19-3.632, P = 0.010). Psychosocial measures were significantly associated with Mpox infection, including higher perceived discrimination (OR = 1.136, 95% CI 1.026-1.258, P = 0.014) and lower self-esteem (OR = 0.962, 95% CI 0.929-0.997, P = 0.034).

conclusionsMpox infection among MSM in China was associated with psychosocial (perceived discrimination, self-esteem) and behavioral (condomless anal sex, partner number, pre-sex substance use) characteristics, with higher odds observed among younger men. Integrating Mpox screening and risk-reduction support into existing HIV/sexually transmitted infection services, alongside anti-stigma and youth-focused outreach, may help address observed disparities.

Indexed as

Health EquityMpox, MonkeypoxSexual BehaviorAdolescentAdultChinaCross-Sectional StudiesHIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedRisk FactorsSurveys and QuestionnairesYoung AdultChinaCross-sectional studyHealth equityHIVMpoxMSMPsychosocial correlatesStigmaSubstance useUnprotected anal intercourse

Identifiers

PMID41709360
PMCPMC12914930

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.