ArticleAdvanced healthcare materials2026
Nanobiosensor Based on Catalytic Palladium Nanoclusters and Oxidases for Bianalyte Electrochemical Determination: Glucose and Ethanol in Sweat.
Article in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Monitoring metabolites through non-invasive methods is revolutionizing clinical analysis, with decentralized and faster tests. Sweat, a readily available biological fluid that requires non-invasive and simple procedures, is emerging as a valuable source of key biomarkers, such as glucose and ethanol. In this work, an enzymatic nanobiosensor for simultaneous determination of glucose and ethanol in sweat samples has been developed. The electrochemical platform consists of two working electrodes onto which Pd nanoclusters (PdNCs) with catalytic activity for the oxygen reduction reaction were deposited. Additionally, each WE was modified either with glucose oxidase (GOx) or alcohol oxidase (AOx). Thus, the simultaneous quantification of both analytes, glucose and ethanol, was performed thanks to the localized decrease in the concentration of dissolved O
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