Evidence map›Paper›PMID 41710194›Full record

ArticleJournal of the Endocrine Society2026

Subclinically low BMD in young men is associated with compromised bone microarchitecture and lower lean mass.

Jenna B Goulart, Christopher K Kargl, Adam J Sterczala, Nicole M Sekel, Livia G Wunderlich, Kelly H Mroz, Mita Lovalekar, Brian J Martin, Pouneh K Fazeli, Jane A Cauley and 4 more

Abstract read
In one paragraph

Article in Journal of the Endocrine Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jenna B GoulartSchool of Health and Rehabilitation Sciences, Department of Sports Medicine, University of Pittsburgh, Pittsburgh, PA 15203-2375, USA.ORCID https://orcid.org/0000-0003-4232-7274
Christopher K KarglSchool of Health and Rehabilitation Sciences, Department of Sports Medicine, University of Pittsburgh, Pittsburgh, PA 15203-2375, USA.
Adam J SterczalaSchool of Health and Rehabilitation Sciences, Department of Sports Medicine, University of Pittsburgh, Pittsburgh, PA 15203-2375, USA.
Nicole M SekelSchool of Health and Rehabilitation Sciences, Department of Sports Medicine, University of Pittsburgh, Pittsburgh, PA 15203-2375, USA.
Livia G WunderlichSchool of Health and Rehabilitation Sciences, Department of Sports Medicine, University of Pittsburgh, Pittsburgh, PA 15203-2375, USA.
Kelly H MrozSchool of Health and Rehabilitation Sciences, Department of Sports Medicine, University of Pittsburgh, Pittsburgh, PA 15203-2375, USA.
Mita LovalekarSchool of Health and Rehabilitation Sciences, Department of Sports Medicine, University of Pittsburgh, Pittsburgh, PA 15203-2375, USA.ORCID https://orcid.org/0000-0002-4536-8656
Brian J MartinSchool of Health and Rehabilitation Sciences, Department of Sports Medicine, University of Pittsburgh, Pittsburgh, PA 15203-2375, USA.
Pouneh K FazeliSchool of Medicine, Division of Endocrinology and Metabolism, University of Pittsburgh, Pittsburgh, PA 15213-2500, USA.ORCID https://orcid.org/0000-0003-1731-2927
Jane A CauleySchool of Public Health, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261-3100, USA.
Thomas J O'LearyBritish Army, Army Health and Performance Research, Andover, Hampshire SO22 6NQ, UK.
Julie P GreevesBritish Army, Army Health and Performance Research, Andover, Hampshire SO22 6NQ, UK.
Kristen J KoltunSchool of Health and Rehabilitation Sciences, Department of Sports Medicine, University of Pittsburgh, Pittsburgh, PA 15203-2375, USA.
Bradley C NindlSchool of Health and Rehabilitation Sciences, Department of Sports Medicine, University of Pittsburgh, Pittsburgh, PA 15203-2375, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: Optimizing bone mass accrual early in life is a strategy for mitigating fracture risk in older age. Objective: This study aimed to identify factors associated with lower than expected bone mass in healthy young adult men. Methods: Data from 39 male participants (21 areal bone mineral density [aBMD] Z scores <-1.0 at either the total hip, femoral neck, or lumbar spine [Lower]; 18 Results: The Lower group was older (age in years: Lower 25 [6]; Con 21 [5]; Conclusion: Men with relatively lower than expected aBMD demonstrated compromised bone microarchitecture and lower lean mass, indicating the importance of targeted intervention for lean mass accrual during young adulthood.

Indexed as

body compositionbone metabolismosteoblast cultureosteoporosis risk

Identifiers

PMID41710194
PMCPMC12910377

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.