ArticleFrontiers in cardiovascular medicine2026
Left atrial function is a strong predictor of exercise intolerance in patients with hypertrophic cardiomyopathy.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Patients with hypertrophic cardiomyopathy (HCM) often experience exercise intolerance. However, the primary determinants of exercise capacity in patients with HCM remain unclear. Objectives: This study aimed to evaluate exercise intolerance in patients with HCM and investigate the associations between exercise capacity and clinical/imaging characteristics, specially focusing on left atrial (LA) function. Methods: This retrospective analysis utilized data from a prospective cohort of adult patients with HCM. Included patients underwent standardized cardiopulmonary exercise testing (CPET) and 3.0T cardiac magnetic resonance (CMR) between May 2012 and May 2025. Exercise capacity was primarily assessed by peak oxygen uptake (Peak VO Results: Among 120 participants [60.8% (73/120) male, mean age: 45.5 ± 14.4 years], 77.8% (91/120) had reduced exercise tolerance (Peak VO Conclusion: LA dysfunction, as reflected by reduced strain, independently predicts impaired exercise capacity in HCM.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.