Evidence map›Paper›PMID 41710410›Full record

ArticleFrontiers in endocrinology2026

Association of apolipoprotein E gene polymorphisms with risk of coronary artery disease in a Han Chinese population at middle and high altitude in China.

Fanrong Zeng, Xinyi Zhang, Meng Zhang, Hongli Liu, Yuan Li, Fan Ye, Xuejiao Chen, Fangyi Zhu, Lihong Zhai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fanrong ZengDongguan Qiaotou Hospital, Dongguan, China.
Xinyi ZhangInstitute of Neuroscience and Brain Disease, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China.
Meng ZhangDongguan Qiaotou Hospital, Dongguan, China.
Hongli LiuQinghai Provincial Cardiovascular and Cerebrovascular Disease Specialist Hospital, Xining, China.
Yuan LiQinghai Provincial Cardiovascular and Cerebrovascular Disease Specialist Hospital, Xining, China.
Fan YeInstitute of Neuroscience and Brain Disease, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China.
Xuejiao ChenInstitute of Neuroscience and Brain Disease, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China.
Fangyi ZhuQinghai Provincial Cardiovascular and Cerebrovascular Disease Specialist Hospital, Xining, China.
Lihong ZhaiInstitute of Neuroscience and Brain Disease, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study investigated the impact of Methods: This retrospective case-control study involved 628 CAD patients and 628 matched controls without CAD. ApoE genotyping was conducted using PCR-chip technology, and genotype and allele frequencies were compared between groups. Multivariate logistic regression analyzed the link between ApoE polymorphisms and CAD risk in populations at middle and high altitudes. Results: The data revealed significant differences in Discussion: These findings validated that the

Indexed as

AltitudeApolipoproteins ECoronary Artery DiseaseGenetic Predisposition to DiseasePolymorphism, GeneticAgedCase-Control StudiesChinaEast Asian PeopleFemaleGene FrequencyGenotypeHumansMaleMiddle AgedRetrospective StudiesApoE protein, humanApolipoproteins EAPOE genecoronary artery disease (CAD)gene polymorphismHan Chineseindependent predictor

Identifiers

PMID41710410
PMCPMC12909196

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.