Evidence map›Paper›PMID 41710546›Full record

ArticleNeuro-oncology advances

Diagnosing growth in low-grade gliomas with and without artificial intelligence-measured longitudinal volume measurements: A retrospective observational study.

Hassan M Fathallah-Shaykh, Houman Sotoudeh, Markus Bredel, Alex Whitley, Jinsuh Kim, Fanny E Morón, Fabio Raman, Nidhal Bouaynaya, Hayat Rahal

Abstract read
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hassan M Fathallah-ShaykhDepartment of Neurology, The University of Alabama at Birmingham, Birmingham, AL (H.M.F.-S.).ORCID https://orcid.org/0000-0002-2690-7685
Houman SotoudehDepartment of Radiology, University of Texas Southwestern, Dallas, TX.
Markus BredelDepartment of Radiation Oncology, University of Miami, Miami, FL.
Alex Whitley-Central Alabama Radiation Oncology, Montgomery, AL.
Jinsuh KimDepartment of Radiology and Imaging Sciences, Emory University, Atlanta, GA.
Fanny E MorónDepartment of Radiology, Baylor College of Medicine, Houston, TX (F.E.M.).
Fabio RamanDepartment of Radiology, Johns Hopkins School of Medicine, Baltimore, MD.
Nidhal BouaynayaDepartment of Computer and Electrical Engineering, Rowans University, -Glassboro, NJ.
Hayat RahalMRIMath, Birmingham, AL.

Funding

Topic #402: Artificial Intelligence-Aided Imaging for Cancer Prevention, Diagnosis, and MonitoringProject Title: An Interpretable Physician-In-The-Loop Al-Aided Software For Tumor Surveillance In Br75N91022C00051 · NCI · MRIMATH, LLC · PI RAHAL, HAYAT · 2022 to 2022
$2.0M
NCI NIH HHS 75N91022C00051
6 · The paper itself

Abstract

Background: Low-grade or grade 2 diffuse gliomas (LGG) infiltrate the brains leading to significant neurological morbidity. This retrospective observational study evaluates the ability of AI-assisted volumetric analysis to correctly detect tumor growth in longitudinal studies of LGG as compared to the standard clinical method. Methods: A total of 56 gliomas and 7 stable FLAIR lesions were included; gliomas were classified as clinical progression ( Results: In the clinical progression group, automatic AI segmentation followed by human review detected tumor growth at a median of 21 months earlier than visual inspection. In the clinically stable group, AI with human review identified growth in 13/22 cases at a median of 23 months earlier than the last magnetic resonance imaging. AI without human review generated similar results but with a 25% false positive and an 8.33% false negative rate. The median time spent by physicians in reviewing, revising, and approving the AI segmentations is 2 minutes. Conclusions: These findings highlight the clinical potential of AI-assisted volumetric analysis followed by physician oversight for the timely detection of tumor progression in LGG patients.

Indexed as

artificial intelligencelongitudinal imaginglow-grade gliomavolumetric analysis

Identifiers

PMID41710546
PMCPMC12909261

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.