Evidence map›Paper›PMID 41710813›Full record

ArticleCase reports in endocrinology2026

Dual Misuse of Insulin in an Adolescent With Type 1 Diabetes: A Case Report and Management Implications.

Sara C Pender, Mohamed Adil Shah Khoodoruth

Abstract read
In one paragraph

Article in Case reports in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Sara C PenderDepartment of Psychiatry, Western University Schulich School of Medicine and Dentistry, London, Ontario, Canada.ORCID https://orcid.org/0009-0009-0436-5721
Mohamed Adil Shah KhoodoruthLondon Health Sciences Centre, London, Ontario, Canada, lhsc.on.ca.ORCID https://orcid.org/0000-0003-3104-7525

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In Canada, nearly one in five children present with diabetic ketoacidosis (DKA) at the time of their first diabetes diagnosis, a serious and potentially life-threatening complication. Adolescence, marked by insulin resistance, fluctuating appetite, and increasing independence, presents unique challenges for diabetes management. Suicidality is more prevalent in adolescents with type 1 diabetes, with higher rates of ideation and attempts compared to peers without the condition. Insulin misuse, whether by omission or deliberate insulin overdose, is increasingly recognized as a maladaptive coping strategy linked to body image concerns, diabetes-related distress, and psychiatric comorbidity, further compounding vulnerability. Case Report: A 15-year-old female with type 1 diabetes mellitus, diagnosed at age 11, was admitted to child and adolescent psychiatry following a suicide attempt by insulin overdose delivered via her Tandem X2 Control IQ insulin pump. She had a history of multiple suicide attempts, typically in the context of acute psychosocial stressors, and recently transitioned to foster care. Biochemistry revealed suboptimal glycemic control (HbA1c 8.5%) and mild metabolic acidosis. A multidisciplinary review led to targeted insulin adjustments and the introduction of a pump passcode lock, restricting unsupervised bolus dosing as a safeguarding measure against insulin overdose. Psychiatric management was optimized, and coordinated aftercare planning was arranged with child protection, endocrinology, and mental health services. Conclusion: This case illustrates insulin manipulation as a means of self-harm in adolescence. The current admission involved a deliberate insulin overdose with mild DKA in the context of a history of insulin omission and more severe DKA episodes. Few published reports describe such dual misuse, underscoring the need to explicitly assess both behaviors in routine care. In this instance, reintroduction of pump therapy with passcode-protected bolus delivery and tailored alarm configurations provided an additional safeguard, highlighting the potential for diabetes technology, when thoughtfully configured, to augment safety alongside psychiatric and psychosocial intervention.

Indexed as

case reportdiabetic ketoacidosis (DKA)hybrid closed-loop insulin pumpself-harmtype 1 diabetes mellitus

Identifiers

PMID41710813
PMCPMC12910172

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