Trial reportESC heart failure2026
Bridging the post-hospitalization gap: a feasibility study of home-based rehabilitation in decompensated heart failure.
Trial report in ESC heart failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06269263 (Pilot Study to Determine Feasibility of Home-based Cardiac Rehabilitation in Patients With Chronic Heart Failure), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pilot Study to Determine Feasibility of Home-based Cardiac Rehabilitation in Patients With Chronic Heart Failure (Pilot-CRHF)
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
introductionPatients hospitalized with acute decompensated heart failure (ADHF) often experience impaired physical function, reduced quality of life (QoL), and loss of independence. While current guidelines recommend rehabilitation, structured programmes are lacking in Germany. Thus, this trial focuses on the feasibility of a structured, home-based rehabilitation programme in pre-frail and frail patients recently hospitalized for ADHF.
methodsThe Pilot-CRHF (trial registry number: NCT06269263) study is a monocentric, single-arm prospective interventional study including multidimensional home-based exercises targeting endurance, strength, and balance. Adherence rate, physical function (6-minute walk test [6MWT], timed-up-and-go [TUG], Berg-Balance-Scale [BBS]) and QoL (Kansas City Cardiomyopathy Questionnaire [KCCQ]) were assessed at baseline and after 12 weeks of intervention.
results30 patients (mean age 79 ± 8; 40% female; 87% NYHA III or IV) were enrolled between March, 2024 and January, 2025. Among those, 43% had heart failure with preserved ejection fraction and 57% left ventricular ejection fraction (LVEF) <50%. 24 patients (80%) completed the programme. After 12 weeks, 6MWT distance improved significantly (220 ± 134 m vs 308 ± 147 m; P < .001). TUG improved only in patients with LVEF <50% (12.1 ± 5.0 s vs 9.7 ± 4.9 s; P = .04). BBS remained unchanged. QoL improved significantly (KCCQ: 56 ± 16 vs 75 ± 19; P < .001).
conclusionHome-based rehabilitation is feasible leading to clinically meaningful improvements in physical function and QoL in pre-frail and frail heart failure patients, particularly those with LVEF. The results support further evaluation in a larger randomized trial.
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