Evidence map›Paper›PMID 41711905›Full record

ReviewCurrent microbiology2026

Microbial Dysbiosis and Pathogenic Interplay in the Gut-Vaginal Axis: Implications for Polycystic Ovary Syndrome: A Critical Review.

Gokul Sudhakaran, A R Sreekutty, Ki Choon Choi, M Valan Arasu, Ajay Guru, S Karthick Raja Namasivayam, Jesu Arockiaraj

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gokul SudhakaranCenter for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.
A R SreekuttyToxicology and Pharmacology Laboratory, Department of Biotechnology, Faculty of Science and Humanities, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu District, Chennai, Tamil Nadu, 603203, India.
Ki Choon ChoiGrassland and Forages Division, National Institute of Animal Science, Rural Development Administration, Cheonan, 31000, Republic of Korea.
M Valan ArasuDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, 11451, Riyadh, Saudi Arabia.
Ajay GuruDepartment of Cariology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
S Karthick Raja NamasivayamCentre for Applied Research, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Tamil Nadu, 602105, India. biologiask@gmail.com.ORCID http://orcid.org/0000-0003-2894-1905
Jesu ArockiarajToxicology and Pharmacology Laboratory, Department of Biotechnology, Faculty of Science and Humanities, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu District, Chennai, Tamil Nadu, 603203, India. jesuaroa@srmist.edu.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PCOS is the most common endocrine condition among reproductive-age women. This disorder causes irregular menstrual periods, increased hair growth, anovulation, and pregnancy difficulties. PCOS affects more than reproductive health. Recent PCOS research has focused on the Gut-Vaginal Axis, stressing the gut-vaginal microbiota reciprocal interaction. Modern society's ubiquitous stress affects hormonal activity. Stress-induced hormonal shifts may alter the vaginal and gut microbiomes These surroundings' microbial populations may contribute to PCOS-related systemic inflammation, insulin resistance, and reproductive difficulties. Stress hormones and microbiome abnormalities are linked with PCOS, but the mechanisms are yet unknown. This study examines how stress hormones affect gut and vaginal microbiomes in PCOS patients.

Indexed as

DysbiosisGastrointestinal MicrobiomePolycystic Ovary SyndromeVaginaFemaleHumans

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.