Evidence mapPaperPMID 41712477Full record

GuidelineHormone research in paediatrics2026

European Society for Paediatric Endocrinology and European Society of Endocrinology Joint Clinical Practice Guidance for Healthcare Transition from Paediatric to Adult Endocrine Care.

Enora Le Roux, Kirstine Stochholm, Martin Fassnacht, Imelda Coyne, Philippe Touraine, Krystallenia I Alexandraki, Malgorzata Wasniewska, Judith P van Eck, Victoria Di Guisto, Amanda Helm and 13 more

Abstract readPractice Guideline
In one paragraph

Guideline in Hormone research in paediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Enora Le RouxAP-HP.Nord - Université Paris Cité, Hôpital Universitaire Robert Debré, Unité d'Épidémiologie Clinique, Inserm, CIC1426, Paris, France, enora.leroux@aphp.fr.
Kirstine StochholmDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Martin FassnachtDepartment of Medicine, Division of Endocrinology and Diabetes, University Hospital, University of Würzburg, Würzburg, Germany.
Imelda CoyneSchool of Nursing and Midwifery, Trinity College Dublin, Dublin, Ireland.
Philippe TouraineDepartment of Endocrinology and Reproductive Medicine, Pitié Salpêtriere Hospital, Sorbonne Université, Paris, France.
Krystallenia I Alexandraki2nd Department of Surgery, Aretaeio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Malgorzata WasniewskaDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.
Judith P van EckDivision of Pediatric Endocrinology, Department of Pediatrics, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Victoria Di GuistoEuropean Society of Endocrinology, Bristol, UK.
Amanda HelmEuropean Society of Paediatric Endocrinology, London, UK.
Elena ValassiEndocrinology Department, Germans Trias i Pujol Hospital and Research Institute, Universitat Internacional de Catalunya (UIC), CIBERER, Unit 747, ISCIII, Badalona, Spain.
Joke MarlierDepartment of Endocrinology, Ghent University Hospital, Ghent, Belgium.
Martine CoolsDepartment of Internal Medicine and Paediatrics, Ghent University, Ghent, Belgium.
Rasha T HamzaPediatric Endocrinology Unit, Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Tommaso AversaDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.
Andrea M IsidoriDepartment of Experimental Medicine, Sapienza University of Rome, Endo-ERN Centre "Azienda Ospedaliero-Universitaria Policlinico Umberto I", Rome, Italy.
Anders JuulDepartment of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Charlotte VerrokenDepartment of Endocrinology, Ghent University Hospital, Ghent, Belgium.
Marie Juul OrnstrupDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Lina ZabulieneInstitute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Kirsten DavidseDivision of Endocrinology, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Stefano CianfaraniDepartment of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.
Sebastian J C M M NeggersDivision of Endocrinology, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, s.neggers@erasmusmc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe transition from paediatric to adult healthcare is a critical period for young individuals with endocrine conditions. Despite numerous published recommendations, Europe still lacks recent, comprehensive, evidence-based, and practically applicable guidelines for endocrine healthcare transition.

objectiveThe aim of the study was to develop European consensus guidance for transition from paediatric to adult care in endocrine conditions through a structured, evidence-based approach.

methodsA systematic literature review identified 351 recommendations from 55 articles (2011-2023). Articles were included if they provided recommendations on the transition from paediatric to adult care for patients with endocrine diseases or general (non-disease-specific) transition guidance. The guidance was developed by a core multidisciplinary group (n = 7) and refined through focus groups with 18 experts from 10 European countries, representing both paediatric and adult care settings. Patient representatives have reviewed and approved it.

resultsThe guidance includes recommendations across 11 domains: structure of transition service, patient empowerment, patient-professional relationship, multidisciplinary team organisation, healthcare provider education, timing and planning, care coordination, management of non-attendance, psychological support, parent/caregiver role, and readiness tools. Each recommendation was rated as either "recommend" (strong) or "suggest" (conditional) based on expert consensus and available evidence.

conclusionThis ESE-ESPE guidance provides a comprehensive, practical framework for endocrine healthcare transition, applicable across different European healthcare settings. The recommendations emphasise structured programs, care coordination, and patient-centred approaches to optimise transition outcomes.

Indexed as

AdolescentClinical practice guidelinesEndocrine conditionsHealthcare transitionYoung adult

Identifiers

PMID41712477
PMCPMC12919983

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.