Evidence map›Paper›PMID 41713649›Full record

ReviewTransplantation and cellular therapy2026

Fertility Preservation in 2026: Current Landscape in Europe and the United States for Children and Adolescents Undergoing Hematopoietic Stem Cell Transplantation - Recommendations on Behalf of the Westhafen Intercontinental Group.

Andrea Jarisch, Seth J Rotz, Alessandro Cattoni, Blandine Courbiere, Scott D Lundy, Kyle E Orwig, Catherine Poirot, Jean-Hugues Dalle, Rachel Phelan, Tamara Diesch-Furlanetto

Abstract readReview
In one paragraph

Review in Transplantation and cellular therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrea JarischDivision of Pediatric Stem Cell Transplantation and Immunology, Department of Children and Adolescents, Frankfurt University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany; EBMT Pediatric Diseases Working Party, Paris, France.
Seth J RotzPediatric Hematology Oncology and Blood and Marrow Transplantation, Cleveland Clinic, Cleveland, Ohio.
Alessandro CattoniPediatric Department, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Blandine CourbiereDepartment of Gynecology-Obstetric and Reproductive Medicine, AP-HM, Hôpital La Conception, Marseille, France; IMBE, Aix-Marseille Univ, Avignon Univ, CNRS, IRD, Marseille, France.
Scott D LundyGlickman Urological Institute, Cleveland Clinic, Cleveland, Ohio.
Kyle E OrwigDepartment of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Catherine PoirotHematology for Adolescents and Young Adults, Hôpital Saint Louis, GHU AP-HP Nord Université Paris Cité, Paris, France; GRECOT (Groupe de Recherche et d'Étude sur la Cryoconservation de l'Ovaire et du Testicule) France.
Jean-Hugues DalleRobert-Debré Academic Hospital, GHU AP-HP Nord Université Paris Cité, Paris, France; EBMT Pediatric Diseases Working Party, Paris, France.
Rachel PhelanCIBMTR (Center for International Blood and Marrow Transplant Research), Medical College of Wisconsin, Milwaukee, Wisconsin; Division of Pediatric Hematology/Oncology/Blood and Marrow Transplant, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address: rphelan@mcw.edu.
Tamara Diesch-FurlanettoDepartment of Pediatric Hematology/Oncology, University Children's Hospital of Basel, Basel, Switzerland; EBMT Pediatric Diseases Working Party, Paris, France.

Funding

Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
NTP INFORMATION SYSTEMS SUPPORT27305C0011 · NIEHS · Z-TECH CORPORATION · 2007 to 2009
$4.3M
Clinical and mechanistic studies defining optimal preparative approaches to infants with IL2RG/JAK3/RAG1/RAG2 SCID: a randomized trial of busulfan dosageU01AI184132 · NIAID · NATIONAL MARROW DONOR PROGRAM · PI JEFFERY J AULETTA, Michael A Pulsipher · 2024 to 2026
$3.2M
BMT Core - Pediatric Transplantation and Cellular Therapy Consortium (PTCTC): Providing Clinical Trial Access For Children With Life Threatening DiseasesUG1HL174426 · NHLBI · NATIONAL MARROW DONOR PROGRAM · PI Leslie S Kean, Heather E Stefanski · 2024 to 2026
$513k
PROVIDE RABBITS, RATS, MICE, HAMSTERS, GERBILS, GUINEA PIGS27307C0011 · NIEHS · PI BOLEN, WAYNE · 2007 to 2007
$500k
NCI NIH HHS U24 CA076518NHLBI NIH HHS UG1 HL174426NIAID NIH HHS U01 AI184132NIEHS NIH HHS 27305C0011NIEHS NIH HHS 27307C0011NIEHS NIH HHS 27398C0011
6 · The paper itself

Abstract

Advances in hematopoietic stem cell transplantation (HSCT) and other cellular therapies have continued to better the long-term outcomes for pediatric patients undergoing these treatments. However, treatment impacts on future fertility can have substantial impact on patient quality of life. Concurrent with improvements in transplantation, fertility preservation (FP) options and outcomes have also evolved. Options such as ovarian tissue cryopreservatation and testicular tissue cryopreservation are now more widely available and can be considered for very young patients. The timing and choice of FP to be offered can be complex and many considerations must be made when counseling patients and families. Cost and access is also variable depending on the country and region in which a patient resides. The aim of this paper is to provide an updated overview of the current strategies and recommendations for FP that should be offered to all children and adolescents undergoing an allo-HSCT. By summarizing contemporary evidence and practices, this paper may provide support to clinicians in delivering equitable, informed, and accessible FP counseling and care for all eligible patients.

Indexed as

CryopreservationFertility PreservationHematopoietic Stem Cell TransplantationAdolescentChildEuropeFemaleHumansMaleQuality of LifeUnited StatesCellular therapyFertilityHSCTPreservationSurvivorship

Identifiers

PMID41713649
PMCPMC13192477

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.