Evidence map›Paper›PMID 41714110›Full record

ArticleRNA (New York, N.Y.)2026

A novel NLP-based method and algorithm to discover RNA-binding protein (RBP) motifs, contexts, binding preferences, and interactions.

Shaimae I Elhajjajy, Zhiping Weng

Abstract read
In one paragraph

Article in RNA (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Shaimae I ElhajjajyDepartment of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01605, USA sielhajjajy@gmail.com zhipingweng@gmail.com.ORCID 0000-0002-7497-5519
Zhiping WengDepartment of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01605, USA sielhajjajy@gmail.com zhipingweng@gmail.com.ORCID 0000-0002-3032-7966

Funding

A Comprehensive Genomic Community Resource of Transcriptional RegulationU24HG012343 · NHGRI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Anshul Kundaje, Zhiping Weng · 2022 to 2026
$4.6M
NHGRI NIH HHS U24 HG012343
6 · The paper itself

Abstract

RNA-binding proteins (RBPs) are essential modulators in the regulation of mRNA processing. The binding patterns, interactions, and functions of most RBPs are not well-characterized. Previous studies have shown that motif context is an important contributor to RBP binding specificity, but its precise role remains unclear. Despite recent computational advances to predict RBP binding, existing methods are challenging to interpret and largely lack a categorical focus on RBP motif contexts and RBP-RBP interactions. There remains a need for interpretable predictive models to disambiguate the contextual determinants of RBP binding specificity in vivo. Here, we present a novel and comprehensive pipeline to address these knowledge gaps. We devise a natural language processing-based method to deconstruct sequences into entities comprising a target

Indexed as

AlgorithmsComputational BiologyRNA-Binding MotifsRNA-Binding ProteinsBinding SitesHumansProtein BindingRNA-Binding ProteinsNLPRBP interactionsRNA-binding proteins

Identifiers

PMID41714110
PMCPMC13182611

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.