Evidence map›Paper›PMID 41715029›Full record

ArticleBMC neurology2026

Turning versus straight walking under dual-task conditions: a preliminary study for identifying mild cognitive impairment and Alzheimer's disease.

Hedieh Mohammadi, Adel Maghsoudpour, Maryam Noroozian, Fatemeh Mohammadian

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Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hedieh MohammadiDepartment of Mechanical Engineering, SR.C., Islamic Azad University, Tehran, Iran.
Adel MaghsoudpourDepartment of Mechanical Engineering, SR.C., Islamic Azad University, Tehran, Iran. a.maghsoudpour@iau.ac.ir.
Maryam NoroozianCognitive Neurology, Dementia and Neuropsychiatry Research Center, Tehran University of Medical Sciences, Tehran, Iran. maryam.noroozian.mn@gmail.com.
Fatemeh MohammadianDepartment of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis preliminary study is the first to systematically compare dual-task turning versus straight walking metrics for detecting cognitive impairment in older adults.

methodsSeventy-five participants, 26 neurotypical (NT), 25 amnestic mild cognitive impairment (aMCI), and 24 mild Alzheimer’s disease (AD), performed a dual-task walk and turn test. Gait and turn features were extracted and compared through two distinct models: walk-phase and turn-phase. Two models were evaluated (walk-phase vs. turn-phase) using a repeated nested cross-validation pipeline.

resultsThe turn-phase model achieved multiclass balanced-accuracy (macro-averaged recall across NT/aMCI/AD) 68.8% vs. 58.8% for the walk-phase (Wilcoxon p < 0.001, Cohen’s d = 0.67), a statistically significant yet clinically modest ~ 10-point gain. Class AUCs favored the turn-phase for AD (0.92 vs. 0.84) and NT (0.88 vs. 0.82), whereas aMCI discrimination was modest for both (≈ 0.63–0.65). Feature interpretation identified gait speed (walk-phase) and peak head speed and peak segmental angle (turn-phase) as the strongest contributors, with medium-to-large Hedges’ g for key turn features.

conclusionsFindings provide proof-of-concept that turn-phase metrics add discriminative information beyond straight walking. Given the modest absolute accuracy and limited aMCI performance, results should be considered preliminary and warrant external validation in larger and more diverse cohorts.

Indexed as

Alzheimer DiseaseCognitive DysfunctionGaitWalkingAgedAged, 80 and overDual-Task TestsFemaleHumansMaleAlzheimer’s diseaseDementiaDual-task testGait analysisMachine learningMild cognitive impairmentSpatial navigationTurn dynamics

Identifiers

PMID41715029
PMCPMC13023128

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.