Incidence of marginal ulcer after one anastomosis gastric bypass versus Roux-en-Y gastric bypass: a comparative study.

Ahmed Abdelsalam, Ahmed Fahmy, Ahmed Saqr, Sherkawi Elsayed, Ahmed Mohamed Salah Eldden Othman Elansary

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Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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Ahmed AbdelsalamGeneral Surgery Department, Kasr Alainy Medical School, Cairo University, Cairo, Egypt. a.abd.elsalam@kasralainy.edu.eg.

Ahmed FahmyGeneral Surgery Department, Kasr Alainy Medical School, Cairo University, Cairo, Egypt.

Ahmed SaqrGeneral Surgery Department, Kasr Alainy Medical School, Cairo University, Cairo, Egypt.

Sherkawi ElsayedGeneral Surgery Department, Kasr Alainy Medical School, Cairo University, Cairo, Egypt.

Ahmed Mohamed Salah Eldden Othman ElansaryGeneral Surgery Department, Kasr Alainy Medical School, Cairo University, Cairo, Egypt.

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6 · The paper itself

Abstract

backgroundAlthough Roux-en-Y gastric bypass (RYGB) has proven to be a safe and effective choice for long-standing weight loss, associated complications have been described. Among them, marginal ulcer (MU) has been recognized as one of the more significant postoperative complications. One-anastomosis gastric bypass (OAGB) has currently been the third most common procedure overall in the world. Similar to RYGB, concerns have emerged for MU risk after OAGB. This study aimed to compare the incidence of MU after RYGB versus OAGB.

methodsThis is a cross-sectional study that included 62 adult patients who underwent RYGB or OAGB and were followed up for a period of two years. The included patients underwent a complete general examination and upper gastrointestinal endoscopy.

resultsThe prevalence of MU in RYGB patients was 19.4%, whereas in OAGB patients, it was markedly lower at 3.2%, with a statistically significant difference (p = 0.045). In the multivariate analysis, the presence of diabetes and the type of surgery (RYGB) were significant predictors for MU.

conclusionMarginal ulcers occurred at a relatively high rate after bypass surgery. OAGB demonstrated a significantly lower incidence of MUs compared to RYGB. Type 2 diabetes mellitus and the RYGB procedure were significant predictors of MU after adjusting for the confounding factors.

Indexed as

Gastric BypassObesity, MorbidPeptic UlcerPostoperative ComplicationsAdultCross-Sectional StudiesFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedMarginal ulcerOne-anastomosis gastric bypassRoux-en-Y gastric bypass

Identifiers

PMID41715048

DOI10.1186/s12893-026-03559-y

PMCPMC12933895

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