Evidence map›Paper›PMID 41716671›Full record

ArticleBioactive materials2026

Microwave thermal supercharging therapy enables selective tumor ablation via low-power radio frequency-responsive nanotopographies.

Wenna Guo, Eun-Seong Kim, Zengzhen Chen, Qingzhou Wang, Qiong Wu, Longfei Tan, Xiangling Ren, Changhui Fu, Laiping Fang, Lifeng Hang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wenna GuoThe Department of Medical Imaging, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, 510317, China.
Eun-Seong KimLaboratory of Molecular Pathology and Cancer Genomics, Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, Republic of Korea.
Zengzhen ChenState Key Laboratory of Cryogenics Science and Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Laboratory of Controllable Preparation and Application of Nanoparticles, Beijing, 100190, China.
Qingzhou WangRF Bio Center, Department of Electronic Engineering, Kwangwoon University, 20 Kwangwoon-ro, Nowon-gu, Seoul, 01897, Republic of Korea.
Qiong WuState Key Laboratory of Cryogenics Science and Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Laboratory of Controllable Preparation and Application of Nanoparticles, Beijing, 100190, China.
Longfei TanState Key Laboratory of Cryogenics Science and Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Laboratory of Controllable Preparation and Application of Nanoparticles, Beijing, 100190, China.
Xiangling RenState Key Laboratory of Cryogenics Science and Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Laboratory of Controllable Preparation and Application of Nanoparticles, Beijing, 100190, China.
Changhui FuState Key Laboratory of Cryogenics Science and Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Laboratory of Controllable Preparation and Application of Nanoparticles, Beijing, 100190, China.
Laiping FangThe Department of Medical Imaging, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, 510317, China.
Lifeng HangThe Department of Medical Imaging, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, 510317, China.
Xianwei MengState Key Laboratory of Cryogenics Science and Technology, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Laboratory of Controllable Preparation and Application of Nanoparticles, Beijing, 100190, China.
Young-Kee ShinLaboratory of Molecular Pathology and Cancer Genomics, Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, Republic of Korea.
Nam-Young KimRF Bio Center, Department of Electronic Engineering, Kwangwoon University, 20 Kwangwoon-ro, Nowon-gu, Seoul, 01897, Republic of Korea.
Limin MaDepartment of Orthopedics, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, China.
Guihua JiangThe Department of Medical Imaging, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, 510317, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lack of accuracy and penetration significantly hinder the clinical use of microwave (MW) thermotherapy. To address this issue, we propose a microwave thermal supercharging system (MTSS) featuring a miniature meta surface grid waveguide aperture antenna and MW-chaperone GaMOF-Co/Ni nanotopographies (GCN NTs) as MW absorbing materials. The meta surface grid waveguide aperture antenna, designed with filled meta surfaces, offers a reduced size, constrained MW beams, and focused energy for precise tumor MW thermotherapy. The MW-chaperone GCN NTs with multiple heterogeneous interfaces and magnetic structures were developed to enhance the dielectric and magnetic loss characteristics and improve MW absorption at medical frequencies (>90 %). Enhancing MW energy delivery to boost thermal conversion efficiency through meta surface grid waveguide aperture antenna innovation is analogous to increasing the air pressure in an engine's intake manifold. This system significantly improved the effectiveness of MW thermotherapy, achieving a 93 % inhibition and 100 % survival

Indexed as

Absorbing materialsDeep-tissueMicrowaveThermotherapyWaveguide aperture antenna

Identifiers

PMID41716671
PMCPMC12914196

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.