Evidence map›Paper›PMID 41716808›Full record

ArticleFrontiers in medicine2026

Novel diagnostic approaches and therapeutic management of mucormycosis: insights from a retrospective monocentric cohort study.

Othman Lemhamdi, Evelyne Willems, Frédéric Baron, Bernard De Prijck, Jo Caers, Antoine Bouquegneau, Julien Guiot, François Cousin, Alexandre Jadoul, Florence Rogister and 3 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Othman LemhamdiDivision of Hematology, Department of Medicine, University Hospital of Liège, Liège, Belgium.
Evelyne WillemsDivision of Hematology, Department of Medicine, University Hospital of Liège, Liège, Belgium.
Frédéric BaronDivision of Hematology, Department of Medicine, University Hospital of Liège, Liège, Belgium.
Bernard De PrijckDivision of Hematology, Department of Medicine, University Hospital of Liège, Liège, Belgium.
Jo CaersDivision of Hematology, Department of Medicine, University Hospital of Liège, Liège, Belgium.
Antoine BouquegneauDivision of Nephrology-Dialysis-Transplantation, Department of Medicine, University Hospital of Liège, Liège, Belgium.
Julien GuiotDivision of Pneumology, Department of Medicine, University Hospital of Liège, Liège, Belgium.
François CousinDivision of Radiology, Department of Medicine, University Hospital of Liège, Liège, Belgium.
Alexandre JadoulDivision of Nuclear Medicine and Oncological Imaging, Department of Medicine, University Hospital of Liège, Liège, Belgium.
Florence RogisterDivision of Otorhinolaryngology, Department of Medicine, University Hospital of Liège, Liège, Belgium.
Frederic FrippiatDivision of Infectiology, Department of Medicine, University Hospital of Liège, Liège, Belgium.
Marie-Pierre HayetteDivision of Microbiology, Department of Medicine, National Reference Centre for Mycosis, University Hospital of Liège, Liège, Belgium.
Adrien De VoeghtDivision of Hematology, Department of Medicine, University Hospital of Liège, Liège, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mucormycosis is a rare, opportunistic fungal infection with high mortality rates, predominantly affecting immunocompromised patients. Its management is challenging due to diagnostic complexity and limited therapeutic options. Methods: This retrospective cohort study analyzed 21 cases of mucormycosis diagnosed at the University Hospital of Liège between July 2018 and August 2023. Clinical, microbiological, and radiological data were evaluated to identify risk factors, treatment modalities, and outcomes. Results: Hematological malignancies (82%) and immunosuppressive therapy (53%) were the most common risk factors. Pulmonary involvement occurred in 94% of cases. Liposomal Amphotericin B was the most frequently used antifungal therapy, and surgery improved outcomes in 50% of cases when it was performed. Despite these measures, the mortality rate on day 84 remained significant at 35%. Conclusion: This study underscores the challenges of managing mucormycosis in immunocompromised patients. The high mortality rate emphasizes the importance of early diagnosis, tailored antifungal therapy, and standardized treatment protocols to improve survival outcomes.

Indexed as

antifungal therapyhematological malignanciesinvasive fungal infectionsMucoralesmucormycosis

Identifiers

PMID41716808
PMCPMC12913173

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.