Effect of behavioural sleep interventions on blood pressure, heart rate, and heart rate variability in adults with poor sleep health: a systematic review, meta-analysis, and meta-regression analysis.

Samiul A Mostafa, Wasim Hanif, George Balanos, Krishnarajah Nirantharakumar, Jason G Ellis, Abd A Tahrani

Abstract readReview

In one paragraph

Review in European heart journal open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samiul A MostafaDepartment of Metabolism and Systems Science, IBR Tower, Level 2, College of Medicine and Health, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.ORCID https://orcid.org/0000-0002-0415-7908

Wasim HanifDepartment of Metabolism and Systems Science, IBR Tower, Level 2, College of Medicine and Health, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

George BalanosSchool of Sport, Exercise and Rehabilitation Sciences (SportEx), University of Birmingham, Edgbaston campus, Birmingham B15 2TT, UK.

Krishnarajah NirantharakumarCentre of Endocrinology, Diabetes and Metabolism (CEDAM), Birmingham Health Partner, Nuffield House, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Edgbaston, Birmingham B15 2WB, UK.

Jason G EllisDepartment of Psychology, Northumberland Building, City Campus, University of Northumbria, Newcastle upon Tyne NE1 8ST, UK.

Abd A TahraniDepartment of Metabolism and Systems Science, IBR Tower, Level 2, College of Medicine and Health, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Poor sleep health is known to negatively impact cardiovascular risk factors, including systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR), and heart rate variability (HRV). Consequently, there is interest in determining the impact of improving sleep on cardiovascular risk. We reviewed studies aimed at improving sleep using (1) Cognitive Behavioural Therapy for Insomnia (CBT-I) and/or sleep hygiene and (2) sleep extension on these risk factors. Methods: Literature searches were performed on MEDLINE, EMBASE, CINAHL, and Cochrane Library. Studies featuring adults ≥ 18years, a sleep intervention and pre and postrisk factor measurements available were included. Studies of obstructive sleep apnoea were excluded. Results: From 21 studies ( Conclusions: Using behavioural sleep interventions led to clinically significant reductions in blood pressure, suggesting addressing poor sleep health could feature in blood pressure management. Future randomized controlled trials are still required. PROSPERO Identification number: CRD42025628290.

Indexed as

Blood pressureHeart rateInterventionMeta-analysisPoor sleepSleep disorder

Identifiers

PMID41716901

DOI10.1093/ehjopen/oeag006

PMCPMC12915584

What Socratic holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.