Evidence map›Paper›PMID 41717020›Full record

ArticleiScience2026

Protective role of PASH-1 in CGG repeat-driven RNA and protein toxicity in FXTAS.

Tsung-Yuan Hsu, Hsin-Ya Yang, Lin-Shiang Hsieh, Kuan-Yen Chen, Guang-Yuh Chiou, Albert Y Chen, Jay Shieh, Noelle D L'Etoile, Paul J Hagerman, Bi-Tzen Juang

Abstract read
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In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tsung-Yuan HsuDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 300093, Taiwan.
Hsin-Ya YangDepartment of Dermatology, University of California, Davis, Davis, Sacramento 95817, USA.
Lin-Shiang HsiehDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 300093, Taiwan.
Kuan-Yen ChenDepartment of Civil Engineering, National Taiwan University, Taipei 106216, Taiwan.
Guang-Yuh ChiouDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 300093, Taiwan.
Albert Y ChenDepartment of Civil Engineering, National Taiwan University, Taipei 106216, Taiwan.
Jay ShiehDepartment of Materials Science and Engineering, National Taiwan University, Taipei 10617, Taiwan.
Noelle D L'EtoileDepartment of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA.
Paul J HagermanDepartment of Biochemistry and Molecular Medicine, University of California, Davis, School of Medicine, Davis, CA 95616, USA.
Bi-Tzen JuangDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 300093, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fragile X-associated tremor/ataxia syndrome (FXTAS) is caused by CGG repeat expansions in

Indexed as

cell biologyNeuroscience

Identifiers

PMID41717020
PMCPMC12915212

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.