Evidence map›Paper›PMID 41717033›Full record

ArticleFrontiers in nutrition2026

Research on the mechanism of cow milk protein dietary intervention in ameliorating systemic chronic inflammation in type 2 diabetes by disrupting the ROS-M1 macrophage axis.

Fumei Zhang, Lin Bai, Heqiang Yang, Jianrong Yang, Zhuxin Sun, Jia Wei, Zilin Qiao, Yumei Wei, Fei Song, Xiaojing Tian and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fumei Zhang *Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Lin Bai *Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Heqiang YangKey Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Jianrong YangSchool of Life Sciences and Engineering, Northwest Minzu University, Lanzhou, China.
Zhuxin SunSchool of Life Sciences and Engineering, Northwest Minzu University, Lanzhou, China.
Jia WeiSchool of Life Sciences and Engineering, Northwest Minzu University, Lanzhou, China.
Zilin QiaoKey Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Yumei WeiSchool of Life Sciences and Engineering, Northwest Minzu University, Lanzhou, China.
Fei SongShengyuan Nutritional Food Co., Ltd., Qingdao, China.
Xiaojing TianKey Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Xiaoxia HuThe Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Recent studies suggest that type 2 diabetes mellitus (T2DM) is characterized by a systemic, low-grade chronic inflammatory state. Although cow milk protein (CMP) has been shown to alleviate this inflammation, its underlying mechanisms remain unclear. Methods: Therefore, we investigated how CMP mitigates systemic chronic inflammation in T2DM using both Results: The Discussion: In conclusion, CMP ameliorates systemic chronic inflammation in T2DM by disrupting the ROS-M1 macrophage vicious cycle.

Indexed as

cow milk proteinmacrophage polarizationoxidative stresssystemic chronic inflammatory responsetype 2 diabetes mellitus

Identifiers

PMID41717033
PMCPMC12913101

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.