Evidence map›Paper›PMID 41717034›Full record

ArticleFrontiers in nutrition2026

Epigenetic and microbiome responses to greens supplementation in obese older adults: results from a randomized crossover-controlled trial.

Laura A Robinson, Aidan M Cavanah, Sarah Lennon, Madison L Mattingly, William Van Der Pol, Kevin W Huggins, Michael W Greene, Michael D Roberts, Andrew D Frugé

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura A RobinsonDepartment of Nutritional Science, Auburn University, Auburn, AL, United States.
Aidan M CavanahDepartment of Nutritional Science, Auburn University, Auburn, AL, United States.
Sarah LennonDepartment of Nutritional Science, Auburn University, Auburn, AL, United States.
Madison L MattinglySchool of Kinesiology, Auburn University, Auburn, AL, United States.
William Van Der PolBiomedical Informatics, The University of Alabama at Birmingham, Birmingham, AL, United States.
Kevin W HugginsDepartment of Nutritional Science, Auburn University, Auburn, AL, United States.
Michael W GreeneDepartment of Nutritional Science, Auburn University, Auburn, AL, United States.
Michael D RobertsSchool of Kinesiology, Auburn University, Auburn, AL, United States.
Andrew D FrugéCollege of Nursing, Auburn University, Auburn, AL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is influenced by genetic, environmental, and lifestyle factors. Preliminary studies suggest that fruit and vegetable-based dietary supplements may reduce inflammation and oxidative stress, key factors in aging. Greens-based supplements typically contain concentrated extracts of leafy greens, fruits, vegetables, and bioactive phytochemicals, providing micronutrients and polyphenols that may influence aging-related pathways. This exploratory study evaluated the effects of a 30-day greens-based supplement on epigenetic markers of aging and metabolic health in adults aged 50-65 years with body mass index (BMI) >30 kg/m

Indexed as

biological agingDNA methylation ageepigenetic clocksgreens supplementgut microbiomenutritional interventionrandomized crossover trial

Identifiers

PMID41717034
PMCPMC12915338

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.