ArticleFrontiers in oncology2026
Association between the prognostic nutritional index and early mortality of AML patients after allogeneic HSCT: a retrospective cohort analysis.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) is an effective treatment for Acute Myeloid Leukemia (AML). The pre-transplantation Prognostic Nutritional Index (PNI) plays a critical role in determining patient prognosis, however, its correlation with mortality within 180 days after SCT is currently unclear. Objective: This study aimed to investigate the association between PNI and mortality within 180 days among AML patients who underwent HSCT. Methods: We conducted a cohort study by retrospectively collecting data from AML patients who underwent HSCT. The PNI was calculated and recorded as serum albumin (g/L) + 5 × peripheral blood lymphocyte count (10 Results: This retrospective cohort study included 477 adult patients with AML. The mean age of the patients was 37.4 ± 11.8 years, with males accounting for 55.6%. The vast majority (79.5%) of patients received transplants from related donors. Among those patients, 13.2% died within 180 days after transplantation. Patients with PNI T1 (30.2-44.6) had a significantly higher adjusted hazard ratio (HR) for mortality (1.52; 95% confidence intervals (CI), 1.17-1.98; Conclusions: The PNI exhibits a L-shaped association with 180-day mortality in AML patients post-HSCT, emerging as a significant predictor with a critical threshold identified at PNI 46. Below this threshold, declining PNI values correlate with increased mortality risk, underscoring its clinical utility in driving nutritional interventions to enhance post-transplant survival outcomes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.