ArticleFrontiers in oncology2026
Association between cancer and cardiovascular disease risk: a cross-sectional study of 241,064 individuals.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Population Estimates and Hypertension and Diabetes Prevalence: Cross-Sectional Quantitative Study Comparing Electronic Health Record-Derived Counts, Census, and Centers for Disease Control and Prevention Population Level Analysis and Community Estimates.JMIR public health and surveillance · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Advances in cancer therapy have improved survival, yielding a larger population of cancer survivors, with cardiovascular disease (CVD) becoming a major chronic health issue among them. However, the association between cancer and CVD risk remains unclear. Methods: This study conducted a cross-sectional analysis utilizing 2023 United States Behavioral Risk Factor Surveillance System (BRFSS) data. Propensity score matching (PSM) balanced the observed covariates between the cancer and non-cancer groups. Univariate and multivariate logistic regression were employed to examine the relationship between cancer history and CVD. Subgroup analyses evaluated this association across different populations. Finally, univariate and multivariate logistic regression identified CVD risk factors among cancer survivors. Results: Before PSM, CVD prevalence was 20.7% in cancer patients, significantly higher than 10.7% in non-cancer individuals. Multivariate logistic regression revealed that cancer remains positively associated with CVD risk even after adjusting covariates (OR = 1.16, 95% CI: 1.12-1.20, P < 0.001). Analysis after 1:2 PSM further validated this association: The prevalence of CVD was higher in the cancer group than in the matched control group (20.7% vs. 18.2%; OR = 1.14, 95% CI: 1.10-1.18, P < 0.001). Except for diabetes and chronic kidney disease (CKD) subgroups, most subgroups of cancer are positively associated with CVD risk (OR > 1, P < 0.05). Among cancer survivors, advanced age, comorbidities (hypertension, diabetes, CKD), depression, and smoking were significantly positively associated with CVD risk, while female sex, aerobic physical activity, and higher income were significantly negatively associated with cardiovascular disease risk. Conclusion: There is a significant positive correlation between cancer and CVD risk, indicating that CVD risk assessment and prevention efforts for cancer survivors should be strengthened.
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