Evidence map›Paper›PMID 41717876›Full record

ReviewCancer2026

Consensus recommendations in the management of jaw (gnathic) osteosarcoma.

Matthew S Dietz, Lara E Davis, Pinki K Prasad, Shauna R Campbell, John D Reith, Mallery R Olsen, Scott E Kilpatrick, Jamie A Ku, Natalie L Silver, Earl P Park and 13 more

Abstract readConsensus StatementReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Matthew S DietzDepartment of Pediatrics, University of Utah and Primary Children's Hospital, Salt Lake City, Utah, USA.
Lara E DavisDepartment of Medicine, Oregon Health and Science University, Portland, Oregon, USA.ORCID https://orcid.org/0000-0002-6480-1611
Pinki K PrasadDepartment of Pediatrics, Louisiana State University Health Sciences Center/Children's Hospital of New Orleans, New Orleans, Louisiana, USA.
Shauna R CampbellDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, Ohio, USA.
John D ReithDepartment of Pathology, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-0542-3040
Mallery R OlsenDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Scott E KilpatrickDepartment of Pathology, Cleveland Clinic, Cleveland, Ohio, USA.
Jamie A KuHead and Neck Surgery, Integrated Surgical Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Natalie L SilverHead and Neck Surgery, Integrated Surgical Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Earl P ParkDepartment of Oral and Maxillofacial Surgery, Louisiana State University Health Sciences Center New Orleans, School of Dentistry, New Orleans, Louisiana, USA.
Elisa TirteiDepartment of Pediatric Onco-Hematology, Regina Margherita Children's Hospital, Turin, Italy.ORCID https://orcid.org/0000-0003-4144-5957
Cristina MeazzaPediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.ORCID https://orcid.org/0000-0002-1875-9563
Erin S MurphyDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, Ohio, USA.
Nicole C MalloryDivision of Pediatric Hematology-Oncology, New York University Langone Health, New York, New York, USA.
Emanuela PalmeriniOsteoncology, Bone, and Soft Tissue Tumors and Innovative Therapies Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.ORCID https://orcid.org/0000-0003-3406-6705
Leo KagerDepartment of Pediatrics, Medical University Vienna and St Anna Children's Cancer Research Institute, St Anna Children's Hospital, Vienna, Austria.ORCID https://orcid.org/0000-0003-4954-6488
Marinka L F HolPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Roelof van EwijkPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Joseph LopezDepartment of Children's Surgery, Division of Pediatric Head and Neck Surgery, Advent Health for Children, Orlando, Florida, USA.
Leighton A ElliottDepartment of Medicine, University of Florida, Gainesville, Florida, USA.
Dale R ShepardDepartment of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, Ohio, USA.
Ajay GuptaDivision of Pediatric Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.ORCID https://orcid.org/0000-0001-6074-9847
Matteo M TruccoDepartment of Pediatrics, Cleveland Clinic Children's, Cleveland, Ohio, USA.ORCID https://orcid.org/0009-0007-4259-2971

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gnathic osteosarcoma (OS), which includes mandibular and maxillary jaw OSs, account for 6%-9% of OS. Single-institutional and multi-institutional retrospective studies, as well as population-level databases, suggest that clinical differences exist among gnathic OS and OS of other sides, including other craniofacial OS. To date, no specific prospective studies of gnathic OS have been reported, and aspects of clinical management are controversial. Some elements of care are aligned with extragnathic OS, e.g., margin negative (R0) surgery, whereas others, such as chemotherapy and radiation, are not clearly defined. The authors reviewed the available literature for the diagnosis, treatment, and supportive/survivorship care patients with gnathic OS and offer consensus statements for the comprehensive management of this rare disease.

Indexed as

Jaw NeoplasmsOsteosarcomaHumanschemotherapyconsensushead and neckjawjaw osteosarcomaradiation

Identifiers

PMID41717876
PMCPMC12921839

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.