Evidence map›Paper›PMID 41717952›Full record

ArticleJournal of the American Heart Association2026

Annual Trends in Risk Factor Control Status at the Time of Ischemic Stroke in South Korea.

Joon-Tae Kim, Ji Sung Lee, Hyunsoo Kim, Beom Joon Kim, Jihoon Kang, Keon-Joo Lee, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim and 33 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors.

Joon-Tae KimDepartment of Neurology, Chonnam National University Hospital Chonnam National University Medical School Gwangju Korea.ORCID 0000-0003-4028-8339
Ji Sung LeeClinical Research Center, Asan Institute for Life Sciences, Asan Medical Center University of Ulsan College of Medicine Seoul Korea.ORCID 0000-0001-8194-3462
Hyunsoo KimDepartment of Neurology, Chonnam National University Hospital Chonnam National University Medical School Gwangju Korea.ORCID 0000-0001-9340-8619
Beom Joon KimDepartment of Neurology, Cerebrovascular Center Seoul National University Bundang Hospital Seongnam Korea.ORCID 0000-0002-2719-3012
Jihoon KangDepartment of Neurology, Cerebrovascular Center Seoul National University Bundang Hospital Seongnam Korea.ORCID 0000-0001-5715-6610
Keon-Joo LeeDepartment of Neurology Korea University Guro Hospital Seoul Korea.ORCID 0000-0002-6571-7091
Jong-Moo ParkDepartment of Neurology, Uijeongbu Eulji Medical Center Eulji University School of Medicine Uijeongbu Korea.ORCID 0000-0002-4199-3024
Kyusik KangDepartment of Neurology, Nowon Eulji Medical Center Eulji University School of Medicine Seoul Korea.ORCID 0000-0002-4021-4439
Soo Joo LeeDepartment of Neurology, Daejeon Eulji Medical Center Eulji University School of Medicine Daejeon Korea.ORCID 0000-0001-8622-7000
Jae Guk KimDepartment of Neurology, Daejeon Eulji Medical Center Eulji University School of Medicine Daejeon Korea.ORCID 0000-0003-1418-0033
Jae-Kwan ChaDepartment of Neurology Dong-A University Hospital Busan Korea.ORCID 0000-0002-1049-5196
Dae-Hyun KimDepartment of Neurology Dong-A University Hospital Busan Korea.ORCID 0000-0001-9761-7792
Tai Hwan ParkDepartment of Neurology Seoul Medical Center Seoul Korea.ORCID 0000-0002-5148-1663
Kyungbok LeeDepartment of Neurology, Soonchunhyang University Seoul Hospital Soonchunhyang University College of Medicine Seoul Korea.ORCID 0000-0003-2663-7483
Jeong-Yoon LeeDepartment of Neurology, Soonchunhyang University Seoul Hospital Soonchunhyang University College of Medicine Seoul Korea.ORCID 0000-0002-4297-1791
Jun LeeDepartment of Neurology Yeungnam University Hospital Daegu Korea.ORCID 0000-0001-8643-0797
Doo Hyuk KwonDepartment of Neurology Yeungnam University Hospital Daegu Korea.ORCID 0000-0001-7541-9226
Keun-Sik HongDepartment of Neurology Inje University Ilsan Paik Hospital, Inje University College of Medicine Goyang Korea.ORCID 0000-0002-4684-6111
Yong-Jin ChoDepartment of Neurology Inje University Ilsan Paik Hospital, Inje University College of Medicine Goyang Korea.ORCID 0000-0001-6965-0771
Hong-Kyun ParkDepartment of Neurology Inje University Ilsan Paik Hospital, Inje University College of Medicine Goyang Korea.ORCID 0000-0002-8120-2469
Byung-Chul LeeDepartment of Neurology Hallym University Sacred Heart Hospital Anyang Korea.ORCID 0000-0002-3885-981X
Kyung-Ho YuDepartment of Neurology Hallym University Sacred Heart Hospital Anyang Korea.ORCID 0000-0002-8997-5626
Mi Sun OhDepartment of Neurology Hallym University Sacred Heart Hospital Anyang Korea.ORCID 0000-0002-6741-0464
Minwoo LeeDepartment of Neurology Hallym University Sacred Heart Hospital Anyang Korea.ORCID 0000-0001-8474-5744
Dong-Eog KimDepartment of Neurology Dongguk University Ilsan Hospital Goyang Korea.ORCID 0000-0002-9339-6539
Dong-Seok GwakDepartment of Neurology Dongguk University Ilsan Hospital Goyang Korea.ORCID 0000-0001-7850-0804
Jay Chol ChoiDepartment of Neurology, Jeju National University Hospital Jeju National University College of Medicine Jeju Korea.ORCID 0000-0002-3550-2196
Jee-Hyun KwonDepartment of Neurology Ulsan University College of Medicine Ulsan Korea.ORCID 0000-0002-5894-3146
Wook-Joo KimDepartment of Neurology Ulsan University College of Medicine Ulsan Korea.ORCID 0000-0001-5290-0623
Dong-Ick ShinDepartment of Neurology Chungbuk National University Hospital, Chungbuk National University College of Medicine Cheongju Korea.ORCID 0000-0001-5770-0268
Kyu Sun YumDepartment of Neurology Chungbuk National University Hospital, Chungbuk National University College of Medicine Cheongju Korea.ORCID 0000-0001-9815-7652
Sung Il SohnDepartment of Neurology Keimyung University Dongsan Hospital, Keimyung University School of Medicine Daegu Korea.ORCID 0000-0002-6900-1242
Jeong-Ho HongDepartment of Neurology Keimyung University Dongsan Hospital, Keimyung University School of Medicine Daegu Korea.ORCID 0000-0002-8235-9855
Hyungjong ParkDepartment of Neurology Keimyung University Dongsan Hospital, Keimyung University School of Medicine Daegu Korea.ORCID 0000-0002-6112-2939
Sang-Hwa LeeDepartment of Neurology Hallym University Chuncheon Sacred Heart Hospital Chuncheon-si Gangwon-do Korea.
Chulho KimDepartment of Neurology Hallym University Chuncheon Sacred Heart Hospital Chuncheon-si Gangwon-do Korea.ORCID 0000-0001-8762-8340
Man-Seok ParkDepartment of Neurology, Chonnam National University Hospital Chonnam National University Medical School Gwangju Korea.ORCID 0000-0002-0637-5394
Wi-Sun RyuArtificial Intelligence Research Center JLK Inc. Seoul Korea.ORCID 0000-0002-2823-5253
Kwang-Yeol ParkDepartment of Neurology, Chung-Ang University College of Medicine Chung-Ang University Hospital Seoul Korea.ORCID 0000-0003-4570-3538
Sung Hyuk HeoDepartment of Neurology Kyung Hee University Hospital, Kyung Hee University College of Medicine Seoul Korea.ORCID 0000-0002-9215-5119
Juneyoung LeeDepartment of Biostatistics Korea University College of Medicine Seoul Korea.ORCID 0000-0001-8073-9304
Jeffrey L SaverDepartment of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine University of California Los Angeles CA USA.ORCID 0000-0001-9141-2251
Hee-Joon BaeDepartment of Neurology, Cerebrovascular Center Seoul National University Bundang Hospital Seongnam Korea.ORCID 0000-0003-0051-1997

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to evaluate secular trends in the control of major risk factors at the time of ischemic stroke to assess the real-world implementation of prevention guidelines and identify areas needing greater clinical attention for improved early stroke outcomes.

methodsWe retrospectively analyzed data from a prospective, multicenter, nationwide registry of consecutive patients with acute ischemic stroke between 2011 and 2022. For risk factor controls of interest, hypertension, diabetes, dyslipidemia, and atrial fibrillation (AF) were considered. Well-controlled risk factors were defined as follows: "well-controlled hypertension": hypertension with prior antihypertensive medication and systolic blood pressure <140 mm Hg on admission; "well-controlled diabetes": prior antidiabetic medication with glycated hemoglobin <7.0%; "well-controlled dyslipidemia": prior statin therapy with low-density lipoprotein cholesterol <100 mg/dL; and "well-controlled AF": presence of AF with prior oral anticoagulant use. Linear trends in control rates were tested via the Cochran-Armitage and linear contrast tests.

resultsAmong 76 962 patients (68.8±13.3 years;men, 59.0%), the adjusted rate of well-controlled hypertension decreased from 35.7% (95% CI, 34.0%-37.5%) in 2011 to 25.5% (95% CI, 24.4%-26.7%) in 2022, whereas well-controlled status improved for diabetes (26.4%-29.4%), dyslipidemia (22.2%-48.6%), and AF (26.0%-55.7%) from 2011 to 2022 (

conclusionsOur study confirmed a continuous increase in prestroke risk factor control, including diabetes, dyslipidemia, and AF, but the rate remained suboptimal at stroke onset. These findings may help inform strategies to improve risk factor management by identifying priority areas that warrant targeted intervention in clinical practice and population-level guidelines.

Indexed as

Atrial FibrillationBrain IschemiaDiabetes MellitusDyslipidemiasHypertensionIschemic StrokeAgedAged, 80 and overFemaleHumansMaleMiddle AgedRegistriesRepublic of KoreaRetrospective StudiesRisk Assessmentacute ischemic strokeannual changeearly outcomerisk factorrisk factor control

Identifiers

PMID41717952
PMCPMC13055717

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.