Evidence map›Paper›PMID 41718495›Full record

ArticleMicrobiology spectrum2026

An experimental approach to investigate extracellular vesicle-mediated transfer of lipids between fungal cells.

Lucas de O Las-Casas, Daniel A Mellon, Bárbara T Bezerra, Cássia M Souza, Flavia C G Reis, Marcio L Rodrigues

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lucas de O Las-CasasInstituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil.
Daniel A MellonInstituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil.
Bárbara T BezerraInstituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil.
Cássia M SouzaInstituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil.
Flavia C G ReisInstituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil.
Marcio L RodriguesInstituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil.ORCID 0000-0002-6081-3439

Funding

An extracellular vesicle component as a candidate to control cryptococcosis.R01AI183314 · NIAID · FUNDACAO OSWALDO CRUZ · PI JOSHUA D NOSANCHUK, Marcio Lourenco Rodrigues · 2024 to 2026
$380k
Conselho Nacional de Desenvolvimento Científico e Tecnológico 402651/2024-3, 404365/2023-0, 304998/2022-2Failsafe FR1-49Fundação Oswaldo Cruz Program for Research Stimulation (PEP)NIH HHS R01AI183314
6 · The paper itself

Abstract

Extracellular vesicles (EVs) are key mediators of communication in fungal populations, but the mechanisms underlying lipid exchange through EVs remain poorly characterized. Here, we describe an experimental approach to visualize lipid transfer between fungal cells using the lipophilic dye FM 1-43. This styryl dye efficiently stained membranous structures in multiple fungal species, including

Indexed as

Extracellular VesiclesFungiLipid MetabolismLipidsBiological TransportCandida albicansCryptococcus neoformansFlow CytometryFluorescent DyesPyridinium CompoundsStaining and LabelingFluorescent DyesLipidsPyridinium Compoundscell biologyCryptococcusextracellular vesicles

Identifiers

PMID41718495
PMCPMC13055321

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.