Evidence mapPaperPMID 41718872Full record

ReviewAdvances in experimental medicine and biology2026

The Potential Roles of Extracellular Vesicles in Wild Animals' Reproduction.

Islam M Saadeldin, Seif Ehab, Abdullah M Assiri

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Islam M SaadeldinInnovation and Research, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. imohamed@kfshrc.edu.sa.ORCID https://orcid.org/0000-0002-7633-730X
Seif EhabBiomedical Sciences Program, University of Science and Technology, Zewail City of Science and Technology, Giza, Egypt.ORCID https://orcid.org/0000-0003-1906-4269
Abdullah M AssiriInnovation and Research, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-2753-5238

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wild animals exhibit diverse reproductive processes crucial for species survival, and recent research has unveiled the integral role of extracellular vesicles (EVs) in orchestrating various aspects of their reproductive survival. This chapter explores the multifaceted involvement of EVs in wild animals' reproduction, encompassing oocyte maturation, spermatogenesis, sperm cryopreservation, preimplantation embryo development, embryo implantation, and the transmission of EVs from male to female. EVs play a pivotal role in oocyte maturation, influencing crucial molecular environments for successful fertilization. Furthermore, the intersection of EVs and spermatogenesis sheds light on how these vesicles contribute to the intricate process of sperm development. Additionally, we explain the impact of EVs on sperm cryopreservation, offering insights into potential advancements in assisted reproductive technologies of wild animal species. Furthermore, the involvement of EVs in preimplantation embryos elucidates their role in shaping the early stages of embryonic development. Notably, the transmission of EVs from male to female is also highlighted, revealing a potential communication channel crucial for successful reproduction. The impact of EVs on improving assisted reproductive technology (ART) outcomes is also explained, showcasing their potential as a tool for enhancing fertility treatments. Additionally, the role of EVs in infertility is explored, providing valuable insights into potential diagnostic and therapeutic avenues. Overall, this chapter underscores the intricate interplay between EVs and various facets of wild animals' reproductive biology. The future implications of understanding EVs in wild animals' reproduction emphasize the need for continued research and innovation in this field.

Indexed as

Animals, WildExtracellular VesiclesReproductionAnimalsCryopreservationEmbryonic DevelopmentFemaleMaleOocytesReproductive Techniques, AssistedSpermatogenesisSpermatozoaAssisted reproductive technologies (ARTs)ConservationsExtracellular vesicles (EVs)Reproductive biologyWild animals

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.