Evidence map›Paper›PMID 41719260›Full record

ArticlePloS one2026

Dietary sodium, potassium, and cardiometabolic risk: A cross-sectional analysis of hypertension in U.S. adults from NHANES 2017-2018.

Xiao Luo, Xuan Zhang, Longfeng Ran, Zhuojun Kang, Xinyu Fu, Xin Mu

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xiao LuoDepartment of Neurology, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu University of Tranditional Chinese Medicine, Chengdu, China.ORCID https://orcid.org/0009-0005-6499-1223
Xuan ZhangDepartment of Neurology, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu University of Tranditional Chinese Medicine, Chengdu, China.
Longfeng RanDepartment of Neurology, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu University of Tranditional Chinese Medicine, Chengdu, China.
Zhuojun KangDepartment of Neurology, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu University of Tranditional Chinese Medicine, Chengdu, China.
Xinyu FuDepartment of Neurology, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu University of Tranditional Chinese Medicine, Chengdu, China.
Xin MuDepartment of Neurology, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu University of Tranditional Chinese Medicine, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationships between dietary sodium and potassium intake and hypertension remain controversial, with recent population-based analyses yielding inconsistent findings. This study aimed to evaluate the associations of sodium and potassium intake with hypertension among U.S. adults and to explore potential interactions with demographic and lifestyle factors.

methodsWe conducted a cross-sectional analysis using data from 5,569 adults aged ≥20 years in the NHANES 2017-2018 cycle. Dietary intake was assessed using 24-hour dietary recall. Hypertension was defined based on self-reported diagnosis. Multivariable logistic regression models were used to estimate adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Restricted cubic spline models examined nonlinear trends, and subgroup analyses were stratified by sex, age, and BMI.

resultsNo significant associations were found between sodium or potassium intake and the odds of hypertension after adjusting for covariates (OR ≈ 1.00, P > 0.05) and findings were consistent when including the Na/K ratio. Results remained stable across sensitivity models and spline analysis. A non-significant inverse trend was observed for dietary fiber intake. Subgroup analyses suggested slightly stronger associations among older adults and individuals with obesity, although interaction terms were not statistically significant.

conclusionIn this nationally representative sample, sodium and potassium intake were not independently associated with hypertension risk. These findings highlight the complexity of diet-blood pressure relationships and the importance of considering broader dietary patterns and individual characteristics in hypertension prevention strategies.

Indexed as

HypertensionPotassium, DietarySodium, DietaryAdultAgedCardiometabolic Risk FactorsCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysOdds RatioUnited StatesYoung AdultPotassium, DietarySodium, Dietary

Identifiers

PMID41719260
PMCPMC12922975

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.