Evidence map›Paper›PMID 41719389›Full record

ArticleScience advances2026

KRAS

Huimin Shao, Fei Xu, Jiangyue Xu, Lingjie Zhou, Yao Wu, Lianjun He, Xueyi Qian, Weijie He, Nanlin Jiao, Yabin Xia and 8 more

RetractedAbstract readRetracted Publication
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Retraction.Science advances · 2026
    Article
  2. Targeted therapeutic strategies forTranslational lung cancer research · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Huimin ShaoPrecision Medicine Centre, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.ORCID 0009-0002-1846-6805
Fei XuPrecision Medicine Centre, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.ORCID 0009-0008-8906-1964
Jiangyue XuDepartment of Thyroid Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Lingjie ZhouSchool of Pharmacy, Wannan Medical College, Wuhu 241002, China.
Yao WuPrecision Medicine Centre, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.
Lianjun HePrecision Medicine Centre, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.
Xueyi QianPrecision Medicine Centre, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.
Weijie HePrecision Medicine Centre, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.
Nanlin JiaoDepartment of Pathology, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.
Yabin XiaDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.
Jun ZhaoDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.
Lili ShengDepartment of Medical Oncology, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.
Guoliang MaoDepartment of Pathology, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.
Tao MaDepartment of Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.
Wei WangDepartment of Gastroenterology, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.
Shaoxiang LuoWuhan Proligand Biotechnology Co. Ltd., Wuhan 430075, China.
Li FuGuangdong Key Laboratory for Genome Stability and Disease Prevention, Department of Pharmacology and Shenzhen International Cancer Center, Shenzhen University Medical School, Shenzhen 518060, China.ORCID 0000-0003-2643-6278
Zhenyu XuPrecision Medicine Centre, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu 241001, China.ORCID 0000-0002-7089-6880

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite advances in chimeric antigen receptor T cell (CAR T cell) therapy for leukemia and lymphoma, solid tumors remain challenging because of limited target specificity and safety concerns. Neoantigens like KRAS

Indexed as

HLA-A2 AntigenImmunotherapy, AdoptiveNeoplasmsReceptors, Chimeric AntigenT-LymphocytesAnimalsCarcinoma, Pancreatic DuctalCell Line, TumorHumansMiceXenograft Model Antitumor AssaysHLA-A2 AntigenReceptors, Chimeric Antigen

Identifiers

PMID41719389
PMCPMC12922744

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.