ArticleUltrasonics sonochemistry2026
Ultrasound-assisted quercetin treatment for mono- and dual-species biofilm eradication in milk: Modeling and optimization using GA-ANN approach.
Article in Ultrasonics sonochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The presence of mono- and dual-species biofilms in food industry poses a critical threat with respect to food security and safety at a global scale. This study explored a novel synergistic eradication strategy using ultrasonication and quercetin, for the eradication of mono and dual-species biofilms of Escherichia coli and Salmonella Typhimurium in milk. The eradication of biofilms was simulated via Response Surface Methodology (RSM) and a Genetic Algorithm-Artificial Neural Network (GA-ANN), taking treatment parameters like ultrasonic amplitude, time and bioactive concentration as inputs variable. Quercetin alone exhibited a significant dose- and time-dependent biofilm inactivation, with the maximum reduction of 2.49 ± 0.08 log for S. Typhimurium and 2.14 ± 0.14 log for E. coli mono-species biofilms, at 4 mg/mL after 4 h of exposure. However, this efficacy decreased in dual-species biofilms, confirming their enhanced structural integrity and resilience. The GA-ANN models showed a better predictive accuracy (R
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.