Evidence map›Paper›PMID 41720151›Full record

ArticleThe Journal of infectious diseases2026

Longitudinal Symptom Transitions Predict Incident Tuberculosis Risk in Serial Active Case Finding.

Esther Jung, José Victor Bortolotto Bampi, Alessandra Moura da Silva, Yiran E Liu, Daniel Henrique Tsuha, Argita D Salindri, Andrea da Silva Santos, Roberto Dias de Oliveira, Julio Croda, Jason R Andrews

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Esther JungDepartment of Medicine, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0001-5073-8749
José Victor Bortolotto BampiFaculdade de Medicina, Federal University of Mato Grosso do Sul, Campo Grande, Brazil.ORCID 0000-0002-1410-7461
Alessandra Moura da SilvaFaculdade de Medicina, Federal University of Mato Grosso do Sul, Campo Grande, Brazil.
Yiran E LiuDepartment of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Daniel Henrique TsuhaFaculdade de Medicina, Federal University of Mato Grosso do Sul, Campo Grande, Brazil.
Argita D SalindriDepartment of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Andrea da Silva SantosDepartment of Health Sciences, Federal University of Grande Dourados, Dourados, Brazil.
Roberto Dias de OliveiraDepartment of Health Sciences, Federal University of Grande Dourados, Dourados, Brazil.ORCID 0000-0001-7996-8011
Julio CrodaFaculdade de Medicina, Federal University of Mato Grosso do Sul, Campo Grande, Brazil.ORCID 0000-0002-6665-6825
Jason R AndrewsDepartment of Medicine, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-5967-251X

Funding

Strategies for tuberculosis control in prisonsR01AI130058 · NIAID · STANFORD UNIVERSITY · PI Jason Randolph Andrews, Julio Henrique Rosa Croda · 2017 to 2026
$5.8M
Mentoring patient-oriented translational research in tuberculosisK24AI182647 · NIAID · STANFORD UNIVERSITY · PI Jason Randolph Andrews · 2024 to 2026
$512k
Brazil's Ministry of HealthBrazil's National Council for Scientific and Technological DevelopmentCNPq 404182/2019-4NIAID NIH HHS K24 AI182647NIAID NIH HHS R01 AI130058U.S. National Institutes of Health K24AI182647U.S. National Institutes of Health R01AI130058
6 · The paper itself

Abstract

Tuberculosis (TB) screening often relies on cross-sectional symptom assessment. To determine the added value of longitudinal symptom monitoring, we conducted a prospective cohort study among 2282 incarcerated men in Brazil. Every 4 months, participants were assessed for symptoms and incident TB (Xpert or culture positive). Compared with remaining asymptomatic, developing symptoms was associated with higher TB risk (aRR 2.31; 95% CI 1.55-3.43), strongest among those with prior radiographic abnormalities (aRR 2.49; 95% CI 1.56-3.97), while remaining symptomatic was not associated (aRR 1.27; 95% CI .72-2.24). Longitudinal symptom monitoring may enhance TB screening in high-risk settings, particularly in complement with radiography.

Indexed as

TuberculosisAdultBrazilHumansIncidenceLongitudinal StudiesMaleMass ScreeningMiddle AgedPrisonersProspective StudiesRisk Factorsactive case findingasymptomaticprisonsscreeningtuberculosis

Identifiers

PMID41720151
PMCPMC13431770

What Socratic holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.