Evidence map›Paper›PMID 41721183›Full record

ArticleInternal and emergency medicine2026

Myocardial injury within 24 hours of Viperidae snake envenomation: a prospective cohort study-a single-center experience from Chongqing, China.

Jing Chen, Jingjing Yin, Dongxu Zhu, Guangcun Song, Qinqin Hu, Yan Du

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Article in Internal and emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing ChenUltrasonography Department of Chongqing Emergency Medical Center, No. 1, Jiankang Road, Liangkou Sub-District, Yuzhong District, Chongqing, 400014, China.ORCID http://orcid.org/0009-0007-5805-2013
Jingjing YinUltrasonography Department of Chongqing Emergency Medical Center, No. 1, Jiankang Road, Liangkou Sub-District, Yuzhong District, Chongqing, 400014, China.
Dongxu ZhuUltrasonography Department of Chongqing Emergency Medical Center, No. 1, Jiankang Road, Liangkou Sub-District, Yuzhong District, Chongqing, 400014, China.
Guangcun SongMedical Imaging Department of Chongqing Emergency Medical Center, Chongqing, 400014, China.
Qinqin HuDepartment of Cardiovascular Medicine of Chongqing Emergency Medical Center, Chongqing, 400014, China.
Yan DuUltrasonography Department of Chongqing Emergency Medical Center, No. 1, Jiankang Road, Liangkou Sub-District, Yuzhong District, Chongqing, 400014, China. 845825927@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial injury following Viperidae snake envenomation significantly worsens clinical outcomes and healthcare burden, yet its early diagnostic predictors remain understudied. In this prospective cohort study from Chongqing, China, we analyzed 75 Viperidae-envenomed patients and 78 healthy controls within 24 h post-bite, assessing electrocardiographic abnormalities, cardiac biomarkers (high-sensitivity cardiac troponin I, creatine kinase), inflammatory markers (C-reactive protein), and echocardiographic right ventricular strain parameters. Results demonstrated a 14.7% incidence of myocardial injury, with 24.0% of patients exhibiting ECG abnormalities, alongside significant elevations in cardiac biomarkers and inflammatory markers (P < 0.05). The absolute values of Right Ventricular Free-wall Strain (RVFWS) and Global Longitudinal Strain (RVGLS) were significantly reduced in envenomed patients, especially in those with concomitant myocardial injury (P < 0.001). Both parameters demonstrated high diagnostic performance: RVFWS-area under the ROC curve 0.846 (95% CI 0.742-0.950); RVGLS-area under the ROC curve 0.825 (95% CI 0.700-0.950). Delayed hospitalization (> 1 h post-bite) independently predicted myocardial injury risk (OR = 1.178, P < 0.05), highlighting the critical need for rapid intervention. These findings identify RVFWS and RVGLS as sensitive early diagnostic markers for cardiac complications and underscore the importance of timely hospitalization to mitigate myocardial injury.

Indexed as

EchocardiographyMyocardial injuryRight ventricular strainTimely hospitalizationViperidae snakebites

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.