Evidence map›Paper›PMID 41721311›Full record

SynthesisBMC pediatrics2026

Prevalence and risk factors for asthma in East Africa: a systematic review and meta-analysis.

Ermias Sisay Chanie, Adam Jaffe, Jahidur Rahman Khan, Nusrat Homaira

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ermias Sisay ChanieDepartment of Pediatric and Child Health Nursing, Debre Tabor University, Debre Tabor, Ethiopia. ermisis1888@gmail.com.
Adam JaffeDiscipline of Pediatric and Child Health, School of Clinical Medicine, UNSW Sydney, Sydney, Australia.
Jahidur Rahman KhanDiscipline of Pediatric and Child Health, School of Clinical Medicine, UNSW Sydney, Sydney, Australia.
Nusrat HomairaDiscipline of Pediatric and Child Health, School of Clinical Medicine, UNSW Sydney, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of childhood asthma is increasing in developing countries, accompanied by numerous risk factors. This leads to substantial asthma related morbidity, mortality and economic consequences. The systematic review and meta-analysis aimed to determine prevalence and risk factors associated with asthma in East Africa, thereby elucidating the asthma burden among children and adolescents in the region.

methodsRelevant articles were identified through searches of five databases ( PubMed, Embase (Ovid), CINAHL (EBSCO), Scopus, and Web of Science), with the PRISMA guideline used for data extraction. Random effects meta-analyses were performed to calculate pooled estimates and associated 95% confidence intervals [CIs]. Heterogeneity between the studies was assessed using Cochrane Q-test and the I

resultsThis meta-analysis encompassed 11 studies involving 20,258 children with asthma across six East African countries. The pooled prevalence of asthma was 15.2% (95% CI: 11.9%,18.5%), with notable variation across countries, ranging from 5.2% (95% CI: 3.3%, 7.1%) in Tanzania to 20.8% (95% CI: 17.6%, 24.0%) in Uganda. Risk factors for asthma included family history of asthma (pooled odds ratio [POR] = 3.1, 95% CI: 1.7, 4.5), environmental exposure(POR = 10.1, 95% CI: 1.3, 19.8), allergy exposure (POR = 3.1, 95% CI: 2.3, 4.0), and exposure to smoking (POR = 2.9, 95% CI: 1.4, 4.3).

conclusionThe prevalence of asthma among children in East Africa was high, and multiple risk factors were associated with it.It appears that strategies and targeted interventions to address specific modifiable factors (e.g., environmental exposure, allergy exposure, and exposure to smoking) should be emphasized. CLINICAL TRAIL NUMBER: CRD42024545007.

Indexed as

AsthmaAdolescentAfrica, EasternChildEast African PeopleHumansPrevalenceRisk FactorsAsthmaChildrenEast AfricaRisk factorsSystematic review and meta-analysis

Identifiers

PMID41721311
PMCPMC12980859

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.