Evidence map›Paper›PMID 41721399›Full record

ArticleBMC women's health2026

Self-management experiences of vaginal toxicities among patients undergoing radical radiotherapy for cervical cancer: a qualitative study.

Xueying Zhang, Jun Wang, Guihao Ke, Yi Zhang, Jiajia Zhang, Jing Zhang, Yaqiong Chen, Xiaoju Zhang

Abstract read
In one paragraph

Article in BMC women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Xueying ZhangDepartment of nursing, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Jun WangDepartment of nursing, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Guihao KeDepartment of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Yi ZhangDepartment of nursing, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Jiajia ZhangDepartment of nursing, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Jing ZhangDepartment of nursing, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Yaqiong ChenDepartment of nursing, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Xiaoju ZhangDepartment of nursing, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. shirlyzxj@126.com.

Funding

the Nursing Research Fund "Huhang" Project of the Oncology Nursing Specialty Committee, Shanghai Anti-Cancer Association SACA-HH202407
6 · The paper itself

Abstract

backgroundCervical cancer is a common gynecologic malignancy, and radiotherapy often induces vaginal toxicities such as vaginitis and stenosis, affecting patients’ physical and psychological well-being. Current research focuses mainly on clinical parameters, with limited attention to patients’ self-management experiences. This study explores their self-management practices to inform targeted nursing strategies.

objectiveTo explore the self-management experiences and existing challenges related to vaginal toxicities among patients undergoing radical radiotherapy for cervical cancer, with the aim of informing the development of tailored management strategies for this population.

methodsA descriptive qualitative design was adopted. Using purposive sampling, 18 patients who had received radical radiotherapy for cervical cancer and returned for follow-up at a tertiary cancer hospital in Shanghai from December 2024 to January 2025 were recruited. Semi-structured individual interviews were conducted, and the data were analyzed using content analysis to extract themes.

resultsThree themes and ten subthemes were identified, including multifaceted challenges in vaginal self-management such as knowledge-related challenges in vaginal self-management, intimacy-related challenges in vaginal self-management, implementation-related challenges in vaginal self-management, environment- and caregiving-related challenges in vaginal self-management; individualized adjustment strategies to cope with self-management dilemmas, including personalized adjustments to vaginal cleansing, self-decision in vaginal dilation management, and self-adjustment in rebuilding intimacy; and internal and external support systems that empower self-management, characterized by the core role of family support, the safeguarding effect of financial support, and emotional connectedness provided by peer support.

conclusionPatients undergoing radical radiotherapy for cervical cancer face multidimensional challenges—cognitive, psychological, and social—in vaginal rehabilitation management. Cognitive biases and poor adherence to vaginal self-management are closely associated with the lack of structured health education. Misconceptions about the disease contribute to sexual psychological distress, while existing nursing care lacks targeted psychological support. Furthermore, insufficient social support, particularly financial burden and limited caregiving capacity, further undermines treatment confidence. Therefore, healthcare providers should establish structured health education systems, strengthen psychological assessment and support, and build comprehensive support networks—including financial, caregiving, and peer support—to enhance patients’ self-management abilities and overall quality of life.

Indexed as

Radiation InjuriesRadiotherapySelf-ManagementUterine Cervical NeoplasmsVaginaVaginal DiseasesAdaptation, PsychologicalAdultAgedChinaFemaleHumansMiddle AgedQualitative ResearchQuality of LifeCervical cancerRadical radiotherapySelf-managementVaginal toxicity

Identifiers

PMID41721399
PMCPMC13032408

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.