Evidence map›Paper›PMID 41721634›Full record

ArticleJournal of pediatric gastroenterology and nutrition2026

Body composition at 2 years of age in moderate and late preterm infants.

Anne H Lafeber, Mark Bosch, Dewi van Harskamp, Nicole R van Veenendaal, Cornelieke S H Aarnoudse-Moens, Johannes B van Goudoever, Femke de Groof

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In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anne H LafeberDepartment of Pediatrics and Neonatology, North West Clinics, Alkmaar, the Netherlands.ORCID https://orcid.org/0009-0003-0083-7310
Mark BoschDepartment of Pediatrics and Neonatology, North West Clinics, Alkmaar, the Netherlands.
Dewi van HarskampAmsterdam UMC, Department of Laboratory Medicine, Core Facility Metabolomics, Laboratory Genetic Metabolic Disease, University of Amsterdam, Amsterdam, the Netherlands.
Nicole R van VeenendaalEmma Children's Hospital Department of Pediatrics, Amsterdam UMC, University of Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Cornelieke S H Aarnoudse-MoensEmma Children's Hospital Department of Pediatrics, Amsterdam UMC, University of Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Johannes B van GoudoeverAmsterdam Reproduction and Development (AR&D), Research Institute, Amsterdam, the Netherlands.
Femke de GroofDepartment of Pediatrics and Neonatology, North West Clinics, Alkmaar, the Netherlands.

Funding

Danone Nutricia Research
6 · The paper itself

Abstract

objectivesModerate and late preterm infants (MLPTI, gestational age 32 0/7-36 6/7 weeks) have altered body composition compared to term-born infants, but data beyond infancy are lacking. This study aimed to assess body composition at 2 years corrected age for prematurity (CA) in MLPTI, compare it to the literature on term-born infants, and identify the association with early-life growth.

methodsMLPTI born between 32 0/7 and 35 6/7 weeks' gestation were included. Body composition at 2 years CA was determined using deuterium-labeled water. Multivariable regression analyses were performed to analyze associations between early-life growth and body composition.

resultsA total of 80 MLPTI were included. Mean percentage body fat mass was 25.3% (standard deviation [SD] 4.30), mean total fat-free percentage 74.7% (SD 3.70), mean fat mass index (FMI) was 3.9 kg/m

conclusionMLPTI have higher fat mass percentages at 2 years CA compared to the literature on term-born infants, while FMI was within range, and fat-free mass index (FFMI) was relatively low. This suggests an altered body composition with reduced fat-free mass instead of excess fat accumulation. This highlights the need for more research on body composition, feeding practices, and cautious weight gain in MLPTI.

Indexed as

Body CompositionChild DevelopmentInfant, PrematureBody Mass IndexChild, PreschoolFemaleGestational AgeHumansInfantInfant, NewbornMalefat massgrowthneonatal outcomesnutrition

Identifiers

PMID41721634
PMCPMC13150944

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.