Evidence map›Paper›PMID 41722021›Full record

ArticleLa Radiologia medica2026

Radiologic maturation and tunnel changes after all-inside versus standard hamstring ACL reconstruction: a prospective comparative study.

Alessandro Carrozzo, Edoardo Monaco, Nicola Carlo Bianco, Etienne Cavaignac, Edoardo Gaj, Riccardo Di Niccolò, Alessandro Annibaldi, Adnan Saithna, Nicola Maffulli

Abstract readComparative Study
In one paragraph

Article in La Radiologia medica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessandro CarrozzoDipartimento di Scienze della Vita, Della Salute e delle Professioni Sanitarie, Link Campus University, Rome, Italy.ORCID http://orcid.org/0000-0003-0700-8139
Edoardo MonacoOrthopedic Surgery Department, Università Degli Studi "La Sapienza", Azienda Ospedaliero-Universitaria Sant'Andrea University Hospital, Via Di Grottarossa 1035-1038, 00189, Rome, Italy. Edoardomonaco76@gmail.com.ORCID http://orcid.org/0000-0003-2377-4829
Nicola Carlo BiancoRadiology Department, Ospedale San Pietro Fatebenefratelli, Rome, Italy.ORCID http://orcid.org/0000-0002-3465-9781
Etienne CavaignacDepartment of Orthopaedic Surgery, Hôpital Pierre Paul Riquet, CHU de Toulouse, Toulouse, France.ORCID http://orcid.org/0000-0003-1043-7567
Edoardo GajOrthopedic Surgery Department, Ospedale Israelitico, Rome, Italy.ORCID http://orcid.org/0000-0002-0108-5347
Riccardo Di NiccolòOrthopedic Surgery Department, Ospedale San Paolo, Civitavecchia, Italy.ORCID http://orcid.org/0000-0001-7986-9232
Alessandro AnnibaldiOrthopedic Surgery Department, Università Degli Studi "La Sapienza", Azienda Ospedaliero-Universitaria Sant'Andrea University Hospital, Via Di Grottarossa 1035-1038, 00189, Rome, Italy.ORCID http://orcid.org/0000-0002-7339-5387
Adnan SaithnaAZBSC Orthopaedics, Scottsdale, AZ, USA.ORCID http://orcid.org/0000-0002-2408-5307
Nicola MaffulliOrthopedic Surgery Department, Università Degli Studi "La Sapienza", Azienda Ospedaliero-Universitaria Sant'Andrea University Hospital, Via Di Grottarossa 1035-1038, 00189, Rome, Italy.ORCID http://orcid.org/0000-0002-5327-3702

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare MRI-based graft maturation and tibial tunnel behavior in all-inside anterior cruciate ligament (ACL) reconstruction using either a quadrupled semitendinosus (ST4) graft or a standard doubled semitendinosus-gracilis (DSTG) technique and to assess mid-term clinical outcomes. MATERIALS AND

methodsThis is a single-center prospective comparative cohort with sequential, non-randomized allocation. Primary imaging endpoints were graft signal-to-noise quotient (SNQ, PD-FS) and tibial tunnel cross-sectional area (CSA) change; clinical endpoints included PROMs and laxity at ≥ 24 months. Reliability was assessed with two independent evaluators and reported using ICC (two-way random, absolute agreement) with 95% CIs.

resultsForty patients (n = 20 per group) completed MRI at 12 months and clinical follow-up at 24 months. SNQ was similar between groups (ST4 1.94 [95% CI 1.28-2.60] vs DSTG 2.84 [1.93-3.75]; difference - 0.90 [- 1.99 to 0.19], P = 0.39). Tibial tunnel widening was lower with ST4 (45.5% [23.7-67.3]) versus DSTG (106.7% [78.3-135.1]); difference - 61.2% [- 95.8 to - 26.6]; P = .02. PROMs and laxity were comparable.

conclusionsAI-ST4 and DSTG ACL reconstruction demonstrated similar graft maturation at 12 months, with less tibial tunnel widening after AI-ST4. At 24 months, clinical outcomes were equivalent between groups; although SNQ and tibial tunnel CSA demonstrated good reproducibility, these imaging differences were not demonstrably associated with functional superiority.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionHamstring TendonsMagnetic Resonance ImagingTibiaAdultFemaleHumansMaleProspective StudiesReproducibility of ResultsTreatment OutcomeACL reconstructionAll-insideGraft maturationMRISignal-to-noise quotientTunnel widening

Identifiers

PMID41722021
PMCPMC13279728

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.