Evidence map›Paper›PMID 41723276›Full record

ArticleCommunications biology2026

Netrin-1 disrupt high-fat-diet-induced adipogenesis via the PPARγ and Wnt/β-catenin signaling pathways.

Hang Shi, Jianghai Tang, Xuemiao Yan, Tingyu Ke, Duo Mao, Deling Kong, Chen Li

Abstract read
In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hang ShiPrecision Medicine Institute, The First Affiliated Hospital of Sun Yat-Sen University, Sun Yat-Sen University, Guangzhou, China.
Jianghai TangInstitute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
Xuemiao YanDepartment of Pathology, Tianjin First Center Hospital, Tianjin, China.
Tingyu KeDepartment of Endocrinology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Duo MaoPrecision Medicine Institute, The First Affiliated Hospital of Sun Yat-Sen University, Sun Yat-Sen University, Guangzhou, China. maod6@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0001-8902-2457
Deling KongState Key Laboratory of Medical Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University, Tianjin, China.ORCID http://orcid.org/0000-0002-2961-9267
Chen LiInstitute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China. cli@bme.pumc.edu.cn.ORCID http://orcid.org/0000-0002-8444-8739

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study reports a detrimental role of adipose-derived Netrin-1 in adipose remodeling. Following an 8-week high-fat feeding period of male transgenic mice lacking adipose Netrin-1 expression (Ntn1

Indexed as

AdipogenesisDiet, High-FatNetrin-1PPAR gammaWnt Signaling PathwayAdipocytesAdipose Tissue, WhiteAnimalsbeta CateninMaleMiceMice, TransgenicObesitybeta CateninNetrin-1Ntn1 protein, mousePPAR gamma

Identifiers

PMID41723276
PMCPMC13035891

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.