ReviewMikrochimica acta2026
Surface plasmon resonance biosensors in the last decade: design strategies and improvements using nanomaterials.
Review in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Surface plasmon resonance (SPR) biosensors have emerged as powerful analytical tools due to their label-free operation, real-time monitoring capability, and broad dynamic detection range, making them highly attractive for clinical, environmental, and food analysis. Despite significant progress over the past decade, the performance of SPR biosensors in real-world applications remains strongly limited by challenges related to sensor construction, surface functionalization, nanomaterial integration, and matrix effects in the analysis of complex samples. This review critically examines recent advances in SPR biosensor design with an emphasis on how construction strategies and functional nanomaterials influence analytical performance. Particular attention is given to the optimization of biomolecule immobilization and nanostructured interfaces as key factors governing sensitivity, selectivity, and robustness. Current limitations associated with nonspecific interactions and complex biological matrices are discussed, highlighting remaining gaps between laboratory performance and practical implementation. By addressing these challenges, this review provides a consolidated perspective on design principles required to improve the reliability and applicability of SPR biosensors, supporting their future development for clinically relevant diagnostics, environmental monitoring, and agronomic analysis.
Indexed as
Identifiers
41723284What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.