Evidence map›Paper›PMID 41723396›Full record

ArticleBMC pulmonary medicine2026

Assessment of cardiopulmonary function: updated two-minute walk distance and walk work equations for obese Chinese populations.

He Zou, Xiaoshu Chen, Jia Zhang, Senxiang Wu, Cong Lin, Yuan Zhu, Xinlei Wu, Lianpin Wu

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Article in BMC pulmonary medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

He Zou *Department of Cardiology, Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China. 476159415@163.com.
Xiaoshu Chen *Department of Cardiology, Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
Jia Zhang *Department of Medical Inspection, Wenzhou Third Clinical Institute, Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
Senxiang WuDepartment of Neurology, Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
Cong LinDepartment of Cardiology, Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
Yuan ZhuDepartment of Nephrology, Wenzhou Third Clinical Institute, Wenzhou Medical University, Wenzhou People's Hospital, Wenzhou, Zhejiang, China.
Xinlei WuDepartment of Cardiology, The Second Affiliated Hospital and Yuying, Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Lianpin WuDepartment of Cardiology, The Second Affiliated Hospital and Yuying, Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. 198019@wzhealth.com.

Funding

Wenzhou Municipal Science and Technology Bureau 2025Y2965
6 · The paper itself

Abstract

backgroundThe two-minute walk test (2MWT) is a practical cardiopulmonary function assessment for obese individuals; however, the current reference equations for the two-minute walk distance (2MWD) are limited, and there are no equations for two-minute walk work (2MWW), reducing its clinical applicability. This study aimed to create new reference equations for the 2MWD and 2MWW in obese Chinese adults.

methodsThis cross-sectional study was conducted at Wenzhou People’s Hospital (May 2019–April 2022) and targeted Chinese individuals aged 18–69 years with a BMI greater than 30 kg/m². Following the 2002 American Thoracic Society (ATS) recommendations, the 2MWT was adapted from the 6MWT. Separate equations for the 2MWD and 2MWW were developed by sex via stepwise multiple regression analysis.

resultsAmong the 288 participants, the mean 2MWD was 185.9 ± 15.68 m, and the mean 2MWW was 15630.7 ± 2136.38 kg·m, with males showing significantly greater results than females did (P < 0.001). Sex-specific equations explained 35% and 61% of the variance for men, and 33% and 62% for women, respectively.

conclusionThe newly developed reference equations for obese Chinese adults enhance the accuracy of cardiopulmonary function assessment and may facilitate more precise monitoring and individualized management of obesity-related cardiopulmonary conditions.

Indexed as

ObesityWalk TestAdolescentAdultAgedBody Mass IndexChinaCross-Sectional StudiesEast Asian PeopleFemaleHumansMaleMiddle AgedReference ValuesYoung AdultCardiopulmonary functionObesityTwo-minute walking distanceTwo-minute walking testTwo-minute walk work

Identifiers

PMID41723396
PMCPMC13032413

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.