Evidence map›Paper›PMID 41723958›Full record

ArticlePoultry science2026

Synergistic impacts of garlic and curcumin on growth performance, carcass characteristics, immunity, antioxidant status, and gut histology of broiler chickens.

Hamada S Saber, Hassan A Khalil, Mohamed M A El-Kashef, Dalia A A Elsayed, Hitham Anas, Hanan M Alharbi, Khairiah M Alwutayd, Mohammad M H Khan, Mohamed E Abd El-Hack, Islam M Youssef

Abstract read
In one paragraph

Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hamada S SaberAnimal Production Department, Faculty of Agriculture, Suez Canal University, Ismailia 41522, Egypt.
Hassan A KhalilAnimal Production Department, Faculty of Agriculture, Suez Canal University, Ismailia 41522, Egypt.
Mohamed M A El-KashefAnimal and Poultry Production Department, Faculty of Environmental Agricultural Sciences, Arish University, Arish, Egypt.
Dalia A A ElsayedDepartment of Poultry Breeding, Animal Production Research Institute, Agricultural Research Center, Dokki, Giza 12618, Egypt.
Hitham AnasAnimal Production Department, Faculty of Agriculture, Al-Azhar University, Assiut branch 71524, Egypt.
Hanan M AlharbiDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Khairiah M AlwutaydDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Mohammad M H KhanDepartment of Biochemistry and Chemistry, Faculty of Biotechnology and Genetic Engineering, Sylhet Agricultural University, 3100 Sylhet, Bangladesh. Electronic address: mehedi2001dbdb@gmail.com.
Mohamed E Abd El-HackDepartment of Industrial Pharmacy, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology (MUST), P.O. Box 77, Giza, Egypt.
Islam M YoussefAnimal Production Systems Research Department, Animal Production Research Institute, Agricultural Research Center, Dokki, Giza 12618, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This investigation estimated the synergistic influences of garlic (Ga) and curcumin (Cu) supplementation on the growth performance, carcass features, immunity, antioxidant capacity, and gut histology of broiler chickens. A total of 300 Cobb 500 chicks were assigned to five dietary treatments: T1 (control) fed only basal diet; T2 fed basal diet supplemented with 0.25% Ga+0.25% Cu, T3: fed basal diet supplemented with 0.25% Ga+0.50% Cu, T4: fed basal diet supplemented with 0.50% Ga+0.25% Cu, and T5: fed basal diet supplemented with 0.50% Ga+0.50% Cu. The maximum inclusion level (0.50% Ga + 0.50% Cu, equivalent to 5 g/kg diet each) produced the greatest final body weight, weight gain and feed conversion ratio despite no change in feed intake according to the results which demonstrated a significant enhancement in growth performance with supplementation. While intramuscular fat dropped in the supplemented groups carcass yield and breast protein content increased significantly suggesting improved nutrient utilization and lean tissue accretion. Furthermore, birds given garlic and curcumin had improved mineral content in their breast meat and higher serum calcium and phosphorus concentrations. As evidenced by increased albumin levels and decreased serum AST and creatinine supplementation improved liver and kidney function indicators. IgG and IgM concentrations were highest in T5 birds, indicating an improvement in immune status. Superoxide dismutase activity was higher and malondialdehyde levels were lower, indicating a reduction in oxidative stress and an improvement in antioxidant defenses. Histologically supplemented birds-especially those in T5-showed longer healthier intestinal villi and well-preserved bursal follicles suggesting enhanced immune organ development and gut integrity. T5 achieved the greatest net revenue and efficiency according to economic evaluation. The results showed that curcumin and garlic work in concert to improve broiler performance, health and profitability. This is a natural substitute for antibiotics.

Indexed as

AntioxidantsChickensCurcuminGarlicImmunity, InnateMeatAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsDietDietary SupplementsDose-Response Relationship, DrugDrug SynergismGastrointestinal TractMaleRandom AllocationAntioxidantsCurcuminAntibiotic alternativesBroilerCurcuminGarlicPhytogenic feed additives

Identifiers

PMID41723958
PMCPMC12945627

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.