Evidence mapPaperPMID 41725942Full record

ReviewFrontiers in cardiovascular medicine2026

Intensified blood pressure control during hospital admission and on discharge: a systematic review and meta-analysis of retrospective cohort studies.

Yevhen Kushnir, Nelson Barrera, Pedro Arias-Sanchez, Erick Romero, Iurii Statnii, Anton Stolear, Kristina Golovataya, Maria Fernanda Solorzano, Salim Baghdadi, Evgeny Shkolnik

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yevhen Kushnir *SBH Health System, Department of Internal Medicine, City University of New York School of Medicine, Bronx, NY, United States.
Nelson Barrera *SBH Health System, Department of Internal Medicine, City University of New York School of Medicine, Bronx, NY, United States.
Pedro Arias-SanchezSBH Health System, Department of Internal Medicine, City University of New York School of Medicine, Bronx, NY, United States.
Erick RomeroSBH Health System, Department of Internal Medicine, City University of New York School of Medicine, Bronx, NY, United States.
Iurii StatniiDepartment of Cardiovascular Diseases, Yale Bridgeport Hospital, Bridgeport, CT, United States.
Anton StolearDepartment of Cardiovascular Diseases, Yale Bridgeport Hospital, Bridgeport, CT, United States.
Kristina GolovatayaMcLaren Greater Lansing, Department of Internal Medicine, Lansing, MI, United States.
Maria Fernanda SolorzanoSBH Health System, Department of Internal Medicine, City University of New York School of Medicine, Bronx, NY, United States.
Salim BaghdadiSBH Health System, Department of Internal Medicine, City University of New York School of Medicine, Bronx, NY, United States.
Evgeny ShkolnikDepartment of Cardiovascular Diseases, Yale Bridgeport Hospital, Bridgeport, CT, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Limited single-center studies suggest that intensified blood pressure (BP) control in patients with asymptomatic elevated BP during non-cardiac admissions may lead to worse outcomes. In this study, we performed a systematic review and meta-analysis exploring the safety of intensified BP control vs. a more conservative approach in patients with asymptomatic elevated BP during non- cardiac admissions and at discharge, focusing on stroke, acute kidney injury (AKI), myocardial infarction (MI), and length of stay (LOS). Methods: Four retrospective propensity score-matched cohort studies ( Results: Intensified BP control was associated with increased odds of stroke (OR 3.77; 95% CI 1.38-10.27; Conclusions: A more conservative approach may be safer in the absence of acute indications for BP lowering. Prospective, randomized inpatient BP trials, particularly those distinguishing interventions initiated during hospitalization vs. at discharge are warranted to clarify causal relationships and guide evidence-based inpatient BP management. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/566609, identifier CRD42024566609.

Indexed as

blood pressureconservative managementinpatient hypertensionintensified managementnon-cardiac hospitalizations

Identifiers

PMID41725942
PMCPMC12916387

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.