Evidence map›Paper›PMID 41726130›Full record

ArticleOpen medicine (Warsaw, Poland)2026

Observational retrospective study on neonatal umbilical cord care: OZOILE on cord separation time and other clinical complications.

Gianfranco Scarpelli, Domenico Montesano, Serena Vella, Maria Lucente, Salvatore Cuzzocrea, Maria Raffaella Ramundo

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gianfranco ScarpelliComplex Operative Unit of Neonatology and Neonatal Intensive Care of the "Annunziata" Hospital - Cosenza Hospital, Cosenza, Italy.
Domenico MontesanoResearch & Development Center, Erbagil Srl, Telese Terme, (BN), Italy.ORCID https://orcid.org/0000-0002-8857-2091
Serena VellaResearch & Development Center, Erbagil Srl, Telese Terme, (BN), Italy.ORCID https://orcid.org/0009-0001-5931-5571
Maria LucenteComplex Operative Unit of Neonatology and Neonatal Intensive Care of the "Annunziata" Hospital - Cosenza Hospital, Cosenza, Italy.
Salvatore CuzzocreaDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy.ORCID https://orcid.org/0000-0001-6131-3690
Maria Raffaella RamundoComplex Operative Unit of Neonatology and Neonatal Intensive Care of the "Annunziata" Hospital - Cosenza Hospital, Cosenza, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Neonatal infections, which continue to be a major cause of morbidity and mortality globally, can be avoided with proper umbilical cord care. There is still no widely recognized standard for cord care despite numerous antiseptic techniques, and the hunt for safe, natural, and efficient substitutes is becoming necessary. In this regard, OZOILE, a formulation based on stable ozonides with wound-healing and antibacterial qualities, may be a viable choice. The purpose of this study was to retrospectively assess the impact of topical OZOILE on the timing of umbilical cord detachment and the avoidance or reduction of infection-related problems in newborns. Methods: The study was conducted in the Complex Operational Unit of Neonatology and Neonatal Intensive Care of the "Annunziata" Hospital-Cosenza (Italy) and included healthy newborns with a gestational age from the 35th to the 41st weeks of gestation, born to mothers with age ranging from 18 to 40 years. Results: Daily application of OZOILE spray oil, directly to the umbilical cord 3 times a day was able the stump fell off in a short time from 5 to 7 days and without any complications. OZOILE reduces secondary alterations of falling umbilical stump. Conclusions: In conclusion, OZOILE intervention could be a good candidate for umbilical cord care.

Indexed as

health careOZOILEstable ozonidesumbilical cord

Identifiers

PMID41726130
PMCPMC12917565

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.