Evidence map›Paper›PMID 41726569›Full record

ArticleEpilepsy currents2026

AES-NINDS Epilepsy Benchmarks Area IV: Comorbidities of Epilepsy - Where Are We and Where Will We Go?

Detlev Boison, Andres M Kanner, Erik Taubøll, Jeffrey Noebels, Delia M Talos

Abstract read
In one paragraph

Article in Epilepsy currents, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Detlev BoisonDepartment of Neurosurgery, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA.ORCID https://orcid.org/0000-0002-7740-5781
Andres M KannerDepartment of Neurology & Comprehensive Epilepsy Center, Miller School of Medicine, University of Miami, Miami, FL, USA.ORCID https://orcid.org/0000-0003-2857-8034
Erik TaubøllDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Jeffrey NoebelsDepartment of Neurology, Neuroscience, and Molecular and Human Genetics, and Developmental Neurogenetics Laboratory, Baylor College of Medicine, Houston, TX, USA.ORCID https://orcid.org/0000-0002-2887-0839
Delia M TalosDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Funding

Seizure-induced enhancement of synaptic signaling regulating tau transmissibility in Alzheimer's DiseaseR01AG077692 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Frances E Jensen, Delia Talos · 2022 to 2026
$3.5M
Therapies for Epilepsy Prevention - Focus on AdenosineR01NS127846 · NINDS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Detlev Boison · 2022 to 2026
$2.1M
Adenosine receptor mediated therapies for SUDEPR01NS103740 · NINDS · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI BOISON, DETLEV · 2018 to 2022
$1.7M
NIA NIH HHS R01 AG077692NINDS NIH HHS R01 NS103740NINDS NIH HHS R01 NS127846
6 · The paper itself

Abstract

Area IV of the 2021 Epilepsy Research Benchmarks aims to establish research goals to limit or prevent adverse consequences of seizures and their treatment across the life span. In this commentary, we will highlight key advances in Area IV. We will focus here on the comorbidities of epilepsy with special emphasis on neuropsychiatry, the endocrine system, and sudden unexpected death in epilepsy, which were discussed at the Epilepsy Benchmarks Area IV Symposium during the Annual Meeting of the American Epilepsy Society in December 2025.

Indexed as

American Epilepsy Society (AES)comorbidities of epilepsyendocrine systemlifespanNational Institute of Neurological Disorders and Stroke (NINDS)neuropsychiatrysudden unexpected death in epilepsy (SUDEP)

Identifiers

PMID41726569
PMCPMC12920149

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.