Evidence map›Paper›PMID 41726646›Full record

ArticleACS omega2026

Nanostructured Lipid Carriers Containing Acridine Derivatives in the Application of Sonodynamic Therapy for the Treatment of Breast Cancer.

Kammila Martins Nicolau Costa, Mariana Rillo Sato, Ricardo Olimpio de Moura, Anthony P McHale, John F Callan, João Augusto Oshiro-Junior

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kammila Martins Nicolau CostaPostgraduate Program in Development and Technological Innovation in Medicines, Federal University of Paraíba, João Pessoa 58051-900, Paraíba, Brazil.
Mariana Rillo SatoPostgraduate Program in Development and Technological Innovation in Medicines, Federal University of Paraíba, João Pessoa 58051-900, Paraíba, Brazil.
Ricardo Olimpio de MouraPostgraduate Program in Development and Technological Innovation in Medicines, Federal University of Paraíba, João Pessoa 58051-900, Paraíba, Brazil.
Anthony P McHaleUlster University, Coleraine BT52 1SA, Northern Ireland, U.K.ORCID https://orcid.org/0000-0003-2397-648X
John F CallanUlster University, Coleraine BT52 1SA, Northern Ireland, U.K.ORCID https://orcid.org/0000-0002-9286-1312
João Augusto Oshiro-JuniorPostgraduate Program in Development and Technological Innovation in Medicines, Federal University of Paraíba, João Pessoa 58051-900, Paraíba, Brazil.ORCID https://orcid.org/0000-0001-7247-1598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Through sonosensitizing agent activation, sonodynamic therapy (SDT) generates an imbalance of reactive oxygen species (ROS) that is potentially damaging to target cells. Acridine derivatives (AD), such as AMTAC compounds (01, 02, 18, 22), present properties of sonosensitizing agents for use in SDT. This work aims to formulate and characterize nanostructured lipid carriers (NLC) containing AD for the application of SDT as a low-invasive breast cancer (BC) treatment. DLS, ELS, SOSG assay, MTT assay,

Identifiers

PMID41726646
PMCPMC12917635

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.