Evidence map›Paper›PMID 41726966›Full record

ArticlebioRxiv : the preprint server for biology2026

Repeat expansions in

Tatiana Ulloa Avila, Jingying Wang, Lydia Adams, Ellen Hu, Alvaro A Beltran, Alexey Kozlenkov, Shreyan Urhekar, Ariana B Marquez Gonzalez, Hun-Goo Lee, J Mauro Calabrese and 4 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tatiana Ulloa AvilaNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0009-0005-7716-9343
Jingying WangNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Lydia AdamsNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-0436-7681
Ellen HuNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Alvaro A BeltranNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-1421-3889
Alexey KozlenkovFriedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Shreyan UrhekarDepartment of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.ORCID 0009-0008-1445-7083
Ariana B Marquez GonzalezNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-0398-1794
Hun-Goo LeeDepartment of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-2840-7684
J Mauro CalabreseDepartment of Pharmacology, University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0002-1213-2540
Stella DrachevaFriedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Adriana S BeltranNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Won MahNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Hyejung WonNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0003-3651-0566

Funding

Interpretable Deep Learning Methods to Investigate Genetics and Epigenetics of Alzheimer's Disease at a Single-Cell ResolutionR01NS128523 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI JING ZHANG · 2022 to 2026
$3.2M
Mechanisms of gene regulation by long noncoding RNAsR35GM153293 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph Mauro Calabrese · 2024 to 2026
$1.9M
In vivo single-cell analysis of Alzheimer's disease-associated regulatory elementsR61AG094646 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WON, HYEJUNG, YAO, BING · 2025 to 2025
$1.2M
BLRD VA I01 BX005585NIA NIH HHS R61 AG094646NIGMS NIH HHS R35 GM153293NINDS NIH HHS R01 NS128523
6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is frequently driven by GGGGCC short tandem repeat (STR) expansions in

Identifiers

PMID41726966
PMCPMC12918968

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.