Evidence map›Paper›PMID 41727172›Full record

ArticlebioRxiv : the preprint server for biology2026

Sexually Dimorphic Response to Dietary Restriction-induced Longevity and Muscle Rejuvenation in

Sonia Sandhi, Hannah Somers, Matthew Cox, Celeste Nobrega, Ryan Seaman, Elizabeth Bakers, Olivia Letchner, Robyn Reeve, Romain Menard, James Godwin and 6 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sonia SandhiHannover Biomedical Research School, Medizinische Hochschule Hannover, Germany.
Hannah SomersMDI Biological Laboratory, United States of America.
Matthew CoxMDI Biological Laboratory, United States of America.
Celeste NobregaMDI Biological Laboratory, United States of America.
Ryan SeamanMDI Biological Laboratory, United States of America.
Elizabeth BakersMDI Biological Laboratory, United States of America.
Olivia LetchnerMDI Biological Laboratory, United States of America.
Robyn ReeveThe Jackson Laboratory, Bar Harbor, United States of America.
Romain MenardMDI Biological Laboratory, United States of America.
James GodwinMDI Biological Laboratory, United States of America.
Anastasia PaulmannHannover Biomedical Research School, Medizinische Hochschule Hannover, Germany.
Aric RogersMDI Biological Laboratory, United States of America.
Dario Riccardo ValenzanoLeibniz Institute on Aging-Fritz Lipmann Institute, Jena, Germany.
Joel GraberMDI Biological Laboratory, United States of America.
Hermann HallerHannover Biomedical Research School, Medizinische Hochschule Hannover, Germany.
Romain MadelaineMDI Biological Laboratory, United States of America.

Funding

The Maine Biomedical Research Network (INBRE)P20GM103423 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI JAMES A COFFMAN · 2012 to 2026
$60.0M
Understanding the role of thyroid hormone signaling during axolotl limb regenerationP20GM104318 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI DRUMMOND, IAIN A. · 2013 to 2023
$23.0M
Regulation of Cellular Behavior in Response to Extracellular CuesP20GM144265 · NIGMS · UNIVERSITY OF MAINE ORONO · PI Benjamin L King · 2023 to 2026
$11.8M
NIGMS NIH HHS P20 GM103423NIGMS NIH HHS P20 GM104318NIGMS NIH HHS P20 GM144265
6 · The paper itself

Abstract

Age-related skeletal muscle decline (sarcopenia) is a major contributor to frailty and mortality during aging, yet the extent to which sex shapes muscle aging and its response to dietary interventions remains poorly understood. Here, we use the short-lived vertebrate

Indexed as

killifishlongevityrejuvenationsarcopeniaskeletal muscle

Identifiers

PMID41727172
PMCPMC12919055

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.