ArticleFrontiers in nutrition2026
Associations of Visceral Adiposity Index and Body Roundness Index with chronic kidney disease in a Hakka population: mediating effect of blood pressure.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to investigate the prevalence of chronic kidney disease (CKD) and explore the associations of the Visceral Adiposity Index (VAI) and Body Roundness Index (BRI) with CKD risk in the Hakka population, while quantitatively assessing the mediating effects of blood pressure indicators. Methods: Data for this study were obtained from a cross-sectional survey conducted in Bobai County, Guangxi, which included 8971 adult participants. Log-binomial regression, robust Poisson regression, and restricted cubic spline regression were used to evaluate the associations between the VAI/BRI and CKD risk. Mediation analysis was further conducted to assess the role of blood pressure parameters in these associations. Results: The overall prevalence of CKD was 12.62% in the study population. In the fully adjusted multivariable model (Model 3), compared with the lowest quartiles (Q1, reference), the highest quartiles (Q4) of both VAI and BRI were significantly associated with increased risks of CKD, with prevalence ratios of 1.61 (95% CI: 1.32-1.98) and 1.26 (95% CI: 1.05-1.52), respectively. Restricted cubic spline analysis revealed nonlinear associations between VAI/BRI and CKD risk, with accelerated risk increments at higher levels of both indices. Mediation analysis revealed that blood pressure indicators significantly mediated the VAI/BRI-CKD relationships, with notably stronger effects observed for BRI (SBP: 42.69%; DBP: 51.16%; MAP: 53.38%) compared to VAI (SBP: 21.4%; DBP: 28.15%; MAP: 28.41%). Additionally, PP exhibited a significant mediating effect only in the BRI-CKD pathway (12.21, 95% CI: 7.28-20.70). Conclusion: The VAI and BRI were independent risk factors for CKD in Hakka Biobank (HKB), with their associations with CKD are partially mediated by blood pressure. Given their ease of measurement and cost-effectiveness, VAI and BRI may serve as practical screening tools for identifying CKD high-risk individuals in community populations, thereby enabling early intervention and targeted prevention strategies of CKD.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.