ArticleFrontiers in nutrition2026
Association between body roundness index and reproductive outcomes in patients with polycystic ovary syndrome: a secondary analysis based on PCOSAct.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Obesity, especially visceral obesity, is highly prevalent in women with polycystic ovary syndrome (PCOS) and may adversely affect fertility outcomes. Body roundness index (BRI) is an anthropometric indicator of visceral adiposity, yet evidence linking BRI to key reproductive outcomes remains limited in PCOS. Methods: This secondary analysis included 998 Chinese women from the Polycystic Ovary Syndrome Acupuncture and Clomiphene Trial (PCOSAct). Baseline BRI was calculated from waist circumference and height measurements, and reproductive outcomes were obtained after interventions. Baseline BRI was calculated from height, weight, and waist circumference and analyzed as quartiles (Q1: < 2.97, Q2: 2.97-3.78, Q3: 3.78-4.87, Q4: ≥ 4.87) and as a continuous variable. Logistic regression models estimated odds ratios (ORs) and 95% confidence intervals (CIs) for ovulation, conception, clinical pregnancy, and live birth, adjusting for interventions, age, systolic and diastolic blood pressure (SBP and DBP). Nonlinearity was assessed using restricted cubic splines (RCS), with model fit compared against linear models using likelihood ratio tests. Results: In total, 780 participants regained ovulation, 320 achieved conception, 218 attained clinical pregnancy, and 205 had a live birth. Higher BRI quartiles were associated with worse anthropometric, metabolic, and hormonal profiles at baseline. In regression analyses, higher BRI quartiles were generally associated with lower odds of reproductive outcomes, with significant trends across quartiles after adjustment. Restricted cubic spline analyses showed no evidence of nonlinearity for ovulation or conception ( Conclusion: Higher BRI was associated with poorer reproductive outcomes in women with PCOS, with evidence of nonlinear associations for clinical pregnancy and live birth. BRI may provide clinically relevant information beyond general adiposity for reproductive risk stratification in PCOS.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.