Evidence map›Paper›PMID 41727435›Full record

ArticleFrontiers in immunology2026

Tachykinin-related peptide signalling is important for the immune response of the mealworm beetle

Natalia Konopińska, Karolina Walkowiak-Nowicka, Grzegorz Nowicki, Maryam Keshavarz, Szymon Chowański, Jens Rolff, Arkadiusz Urbański

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Natalia KonopińskaDepartment of Animal Physiology and Developmental Biology, Faculty of Biology, Adam Mickiewicz University, Poznań, Poland.
Karolina Walkowiak-NowickaDepartment of Animal Physiology and Developmental Biology, Faculty of Biology, Adam Mickiewicz University, Poznań, Poland.
Grzegorz NowickigenXone S.A., Złotniki, Poland.
Maryam KeshavarzEvolutionary Biology, Institute for Biology, Freie Universität Berlin, Berlin, Germany.
Szymon ChowańskiDepartment of Animal Physiology and Developmental Biology, Faculty of Biology, Adam Mickiewicz University, Poznań, Poland.
Jens RolffEvolutionary Biology, Institute for Biology, Freie Universität Berlin, Berlin, Germany.
Arkadiusz UrbańskiDepartment of Animal Physiology and Developmental Biology, Faculty of Biology, Adam Mickiewicz University, Poznań, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Insects possess a well-developed innate immune system, which encompasses both cellular and humoral mechanisms. On the basis of the similarities in neuropeptide actions between insects and vertebrates, we assume that neuropeptides such as tachykinin-related peptides ( Methods: In this study, we examined how immune activation affects the expression of genes encoding TRP precursors and receptors ( Results: Our results revealed two important insights. First, after activation of the immune system, Discussion: Our findings highlight a compelling association between the TRP and immune regulation in

Indexed as

Insect ProteinsSignal TransductionTachykininsTenebrioAnimalsImmunity, HumoralImmunity, InnateNeuropeptidesReceptors, TachykininInsect ProteinsNeuropeptidesReceptors, TachykininTachykininsinsect cytokinesinsect humoral responseinsecticidesinsect immunityneuropeptides

Identifiers

PMID41727435
PMCPMC12916423

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.